镰状细胞病(sickle cell disease)是指红细胞含有血红蛋白s(hbs)的一种常染色体显性遗传的溶血性疾病。本病有三种类型: ①hbs的纯合子称为镰状细胞性贫血; ②杂合子称为镰状细胞特征(sickle cell trait); ③hbs与地中海贫血或其他异常hb基因组合成的双重杂合子称为混合型镰状细胞综合征。
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
疾病介绍 镰状细胞病(sickle cell disease)是指红细胞含有血红蛋白S(HbS)的一种常染色体显性遗传的溶血性疾病。本病有三种类型:①HbS的纯合子称为镰状细胞性贫血;②杂合子称为镰状细胞特征(sickle cell trait);③HbS与地中海贫血或其他异常Hb基因组合成的双重杂合子称为混合型镰状细胞综合征。 本病多见于非洲和...
Sickle cell disease is caused by a mutation in your child’s genes, making blood cells turn into little crescents instead of a round shape. Children inherit this trait from their parents. Read more + How is sickle cell disease in children treated? Sickle cell disease can cause body aches a...
This article explores Sickle Cell Disease and Sickle Cell Trait. These are hereditary conditions that affect thousands of people in the UK and abroad. The disease tends to occur in people of Afro-Caribbean or Mediterranean descent. The specific...
they are unaffected by the abnormal gene but may pass on a risk of sickle-cell disease to their children.3If two people with sickle-cell trait have children, those children have a one in four chance of having sickle-cell disease, a one in four chance of being completely unaffected, and ...
If a child is born with one defective hemoglobin-beta gene, they may become acarrierof the disease. Carriers usually don’t develop SCD symptoms. But they can pass the disease on to their children if their partner also carries the sickle cell trait. ...
Sickle Trait and Sickle Cell Disease Medical Author: Benjamin Wedro, MD, FACEP, FAAEM Medical Editor: Melissa Conrad Stöppler, MD What is sickle cell trait? People can dream, but their road to success can be derailed in the most unusual ways, perhaps none as strange as that which ...
Define Sickle-cell trait. Sickle-cell trait synonyms, Sickle-cell trait pronunciation, Sickle-cell trait translation, English dictionary definition of Sickle-cell trait. n. A hereditary condition, usually harmless and without symptoms, in which an indivi
Sickle cell anemia is a lethal condition that threatens life. However, there may be a selective advantage to being a sickle cell carrier (trait) if the person resides in an area of the world where malaria is very common. The advantage a person with sickle cell trait has over a non-...