镰状细胞病(sickle cell disease)是指红细胞含有血红蛋白s(hbs)的一种常染色体显性遗传的溶血性疾病。本病有三种类型: ①hbs的纯合子称为镰状细胞性贫血; ②杂合子称为镰状细胞特征(sickle cell trait); ③hbs与地中海贫血或其他异常hb基因组合成的双重杂合子称为混合型镰状细胞综合征。
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
sickle cell diseasesickle cell genePrevalenceIncidenceAnemiaHbFHbSMakkahSaudi ArabiaAims and Objectives: To detect the prevalence of sicklecell trait among primary school children(boys and girls) in Makkah city. Patients & Methods: 3980 SaudiChildren (2104 boys and 1876 girls) at the age of 6-12...
sickle cell tlait 【医】 镰状细胞特性 sickle cell 镰刀形红细胞,镰形(状)细胞,镰状红细胞,镰状细胞 sickle cell anemia 镰形细胞贫血,镰状细胞血症,黑里克氏贫血 sickle cell disease 镰刀形红细胞(贫血)病,镰状细胞(贫血)病 相似单词 sickle cell n. 【医】镰状红细胞 trait n. (人的个性的)特...
疾病介绍 镰状细胞病(sickle cell disease)是指红细胞含有血红蛋白S(HbS)的一种常染色体显性遗传的溶血性疾病。本病有三种类型:①HbS的纯合子称为镰状细胞性贫血;②杂合子称为镰状细胞特征(sickle cell trait);③HbS与地中海贫血或其他异常Hb基因组合成的双重杂合子称为混合型镰状细胞综合征。 本病多见于非洲和...
If a child is born with one defective hemoglobin-beta gene, they may become acarrierof the disease. Carriers usually don’t develop SCD symptoms. But they can pass the disease on to their children if their partner also carries the sickle cell trait. ...
Sickle Cell Trait—Neglected Opportunities in the Era of Genomic Medicine Catherine Taylor, MB, BChir1; Patricia Kavanagh, MD2; Barry Zuckerman, MD2 Author Affiliations JAMA. 2014;311(15):1495-1496. doi:10.1001/jama.2014.2157 Full Text The use of genomics to prevent and treat disease is co...
sickle cell diseasephr. 镰状细胞病 sickle cell anemia镰形(状)细胞性贫血,镰状细胞性贫血 sickle cell hemoglobin镰刀细胞血红蛋白 sickle cell trait镰形细胞(遗传)特性 sickle cell anaemia镰刀状细胞(红血球)贫血 sickle cell disease镰刀形红细胞(贫血)病,镰状细胞(贫血)病 ...
It was positive in 242 samples, giving a prevalence of 25.5% for sickle cell disease. On subjecting the positive blood samples to electrophoresis, the proportion of sickle cell trait and sickle cell disease was found to be 92% and 8% respectively. Then electrophoresis was done in 64 parents...
(HealthDay)—Both sickle cell disease and the condition known as sickle cell trait are genetic blood diseases: You're born with one or the other because of the genes inherited from your parents. Beyond that, the two conditions vary considerably.