Sickle cell disease (SCD) is the most prevalent hemoglobinopathy in the USA. It has been reported that children with SCD have an increased risk for sleep problems including sleep-disordered breathing (SDB) compared to the general pediatric population. These children are also at an increased risk ...
Prevalence In some parts of Africa, 45% of the population is heterozygous for the βS gene, in the USA and Caribbean about 8% carry one βS gene. Incidence of homozygous sickle cell disease in the USA is 1 in 625 births. Prevalence is lower in the Mediterranean basin, Saudi Arabia, an...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB, which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 and 400,000 neonates globally each year, the majority in sub-Saharan Africa. Ha
Gaston4, Kwaku Ohene‑Frempong5, Lakshmanan Krishnamurti6, Wally R. Smith7, Julie A. Panepinto8, David J. Weatherall9, Fernando F. Costa10 and Elliott P. Vichinsky11 Abstract | Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB...
We provide an updated assessment of trends in sickle cell disease (SCD)–related mortality, a significant source of mortality in the United States among black persons, using 1979 to 2017 US mortality data. Methods SCD-related deaths were identified with International Classification of Diseases codes...
Sickle Cell DiseasePregnancyHospitalComplications and NeonateThis review article has been conducted in order to evaluate the way of managing sickle cell diseases in African countries. Reviews of four researches have beendoi:10.2139/ssrn.3144026Yadufashije, Dr. Callixte...
Hemoglobin, sickleSickle cell traitThis prospective study was conducted to examine the prevalence of cholelithiasis in sickle cell disease and the relationship of its frequency to age and hematological parameters. Sixty-five patients with sickle cell disease attending Salmaniya Medical Center were ...
This invention provides a method of treating a subject afflicted with sickle cell disease which comprises administering to the subject an amount of an antiviral agent effective to i
Aim: To evaluate the manifestations of sickle cell disease on the orofacial complex through a review of current literature concerning prevalence of dental caries, periodontal disease, temporomandibular joint disorders and radiographic alterations of maxillofacial bones. Methods: Full-text papers retrieved fro...