METHODS: Focusing on the pediatric age group attending a clinic at the Akola Government Medical College, Akola, Maharashtra State, India, a cross-sectional assessment of 91 patients with sickle cell disease was performed during one week in March 2015. RESULTS: Of the 91 patients, there were ...
Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB, which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 and 400,000 neonates globally each year, the majority in sub-Saharan Africa. Haemoglobin molecules that include mutant ...
PRIMER Sickle cell disease Gregory J. Kato1, Frédéric B. Piel2, Clarice D. Reid3, Marilyn H. Gaston4, Kwaku Ohene‑Frempong5, Lakshmanan Krishnamurti6, Wally R. Smith7, Julie A. Panepinto8, David J. Weatherall9, Fernando F. Costa10 and Elliott P. Vichin...
ImportanceSickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within capillary beds, resulting in sickle-shaped red blood cells, progressive multiorgan damage, and increased mortality. An estimated 300 000 infants ...
What is Sickle Cell Disease? Sickle cell disease is a group of genetic blood disorders. You may be more likely to have sickle cell disease if your family came from sub-Saharan Africa, South America, Central America, the Caribbean, Saudi Arabia, India, or some Mediterranean countries such as...
Sickle cell disease in India Sickle cell disease (SCD) poses a considerable health burden in India. This review focuses on the recent initiatives to understand the variable phenotypes,... R Colah,M Mukherjee,K Ghosh - 《Current Opinion in Hematology》 被引量: 130发表: 2014年 Sickle cell ...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Sickle cell diseaseThe clinical manifestation in sickle cell disease (SCD) patients varies from one individual to another due to factors like the presence of alpha-thalassaemia mutation, foetal haemoglobin, and 尾-globin gene haplotype. The present study enumerates the clinical profile of sickle cell...
Central India has a huge population of sickle cell disease patients. Though predicted SS in the region is 22–44 %, 81 homozygous of sickle cell patients reported during study period of Jan 2003–Dec 2005. The clinical course of these patients is characterized in most of the cases by ...
G6PD deficiency and sickle cell disease in India 来自 ResearchGate 喜欢 0 阅读量: 12 作者: Bisnu prasad Dash 摘要: The presence of abnormal haemoglobin particularly the sickle haemoglobin (HbS) in Orissa state is known. The double heterozygotes for sickle cell and beta thalassaemia as well ...