This delivery system is composed of an HCC-targeting lipid layer and esterase-responsive cationic polymer, a poly{N-[2-(acryloyloxy)ethyl]-N-[p-acetyloxyphenyl]-N} (PQDEA) condensed shSLC7A11 core (GLPQDEA/shSLC7A11). After intravenous (i.v.) injection, GLPQDEA/shSLC7A11 quickly ...
ＳＬＣ７Ａ１１基因ＳｈＲＮＡ表达载体的构建及喉癌稳定细胞株的筛选郭有新１ꎬ㊀陈宝刚１ꎬ㊀管㊀华１ꎬ㊀刘建伟１ꎬ㊀郭靖涛１ꎬ㊀李建辉１ꎬ㊀张㊀红２ꎬ㊀马志红１ (１.承德医学院第二附属医院耳鼻喉科ꎬ㊀河北㊀承德㊀０６７０００ ２.首都医科大学附属北京同仁医院ꎬ㊀...
CAS号: 英文名: pLVX-U6-SLC7A11(human)-shRNA1-PGK-EGFP-Puro 英文别名: 中文名: PLVX-U6-SLC7A11(HUMAN)-SHRNA1-PGK-EGFP-PURO 中文别名: PLVX-U6-SLC7A11(HUMAN)-SHRNA1-PGK-EGFP-PURO CBNumber: CB813283621 分子式: 分子量: 0 MOL File: Mol file ...
CAS号: 英文名: pLVX-U6-SLC7A11(human)-shRNA2-PGK-EGFP-Puro 英文别名: 中文名: PLVX-U6-SLC7A11(HUMAN)-SHRNA2-PGK-EGFP-PURO 中文别名: PLVX-U6-SLC7A11(HUMAN)-SHRNA2-PGK-EGFP-PURO CBNumber: CB613302706 分子式: 分子量: 0 MOL File: Mol file ...
目的:评价SLC7A11在右美托咪定预处理减轻小鼠肠缺血再灌注损伤引起铁死亡中的作用.方法:24只雄性健康SPF级C57BL/6J小鼠,8周龄,体质量22～25 g,随机数表法分成4组:假手术组(S组),肠缺血再灌注组(Ⅱ/R组),右美托咪定组(DEX组),右美托咪定+SLC7A11抑制剂组(DIKE组),每组6只.夹闭肠系膜上动脉(su-perior...
与OGD/R组比较,Gen各浓度组细胞LDH释放率,MDA含量,Fe2+水平,ROS水平和TFR1蛋白表达水平显著降低(P<0.05),而细胞增殖活性,SOD活性,GSH水平,SLC7A11和GPX4蛋白表达水平显著升高(P<0.05),其中以H-Gen组最为显著(P<0.05).结论Gen可抑制OGD/R诱导的SH-SY5Y细胞氧化应激与铁死亡,其作用机制可能与激活SLC7A11/GPX4...
et al. 579 Bilirubin Upregulates Gene Expression of Slc7A11 and Increases Cystine Uptake Mediated by System Xc- in Sh-Sy5Y Neuroblastoma Cells. Pediatr Res 68 (Suppl 1), 297 (2010). https://doi.org/10.1203/00006450-201011001-00579 Download citation Issue DateNovember 2010 DOIhttps://doi....
579 Bilirubin Upregulates Gene Expression of Slc7A11 and Increases Cystine Uptake Mediated by System Xc- in Sh-Sy5Y Neuroblastoma CellsPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from ...
C-FOS inhibition promotes pancreatic cancer cell ferroptosis by transcriptionally regulating the expression of SLC7A11 Cellular proto-oncogene C-Fos forms the AP-1 transcription factor by dimerizing with proto-oncogene c-Jun; this factor upregulates the transcription of gen... S Wang,H Yu,P Guo...
579 BILIRUBIN UPREGULATES GENE EXPRESSION OF SLC7A11 AND INCREASES CYSTINE UPTAKE MEDIATED BY SYSTEM XC- IN SH-SY5Y NEUROBLASTOMA CELLS P.J. Giraudi, C. Bellarosa, C. Coda-Zabetta, C. Tiribelli Liver Research Center (CSF), Trieste, Italy Background and aims: Severe neonatal ...