In an effort to further de(R)ne this relationship, (R)ve full- length zebra(R)sh cDNAs, fth1, slc3a2, prkri, cd81, and pc, as well as one putative human gene, DBX were identi(R)ed and their map positions ascertained. These six genes, along with men1, fgf3 and cycd1 de(R...
目的探讨SLC3A2对人神经母细胞瘤SH-SY5Y细胞铁死亡的调控作用.方法使用SH-SY5Y细胞株构建SLC3A2基因敲低细胞模型SLC3A2^(KD),SLC3A2基因过表达细胞模型SLC3A2^(OE),及敲低后过表达细胞模型SLC3A2^(KD+OE).用铁死亡特异性诱导剂Erastin分别处理正常SH-SY5Y细胞,SLC3A2^(KD)细胞,SLC3A2^(OE)细胞和SLC3A2...