However, whether the PD-L1/PD-1-SHP-1 pathway mediates the analgesic and anti-inflammatory effects of EA in inflammatory pain remains unclear. Here, we observed that EA reversed the complete Freund's adjuvant (
通路(Pathway) Protease/Metabolic Enzyme--Phosphatase 分子式(Formula) C21H13ClF3N3O2 分子量(Molecular Weight) 431.8 外观(Appearance) 粉末 纯度(Purity) ≥98% 溶解性(Solubility) 溶于DMSO 结构式(Structure) 细胞实验(体外实验) SC-43(0-10μM)以剂量依赖方式抑制胆管癌细胞(HuCCT-1、KKU-100和cgca)的...
7.Nagai, M., et al. Roles of inflammation and the activated protein C pathway in the brain edema associated with cerebral venous sinus thrombosis. Stroke 41, 147-152 (2010). 8.Clarkson, A.N., Sutherland, B.A. ...
3.8. Effect of YSTB-C on FcγRIIb/Lyn/SHP-1 pathway regulation in ST486 cells Since FcγRIIb signalling pathway is crucial for the proliferation, apoptosis and activation of B cells [20], investigation on whether the effect of YSTB-C is correlated with the FcγRIIb/Lyn/SHP-1 pathway...
(2017). 45.liang, w., et al. interleukin-5 deletion promotes sepsis-induced m1 macrophage differentiation, deteriorates cardiac dysfunction, and exacerbates cardiac injury via the nf-kappab p65 pathway in mice. biofactors 46, 1006-1017 (2020). 46.jung, c.s., lange, b., zimmermann, m. ...
(PFKP) through the AKT–β-catenin pathway. The increase in PFKP elevates energy metabolic activities and, as a consequence, enhances the sensitivity of LSCs to chemotherapeutic agents. Moreover, the upregulation of PFKP promotes MYC degradation and, consequently, reduces the immune evasion ...
Currently, the pathway upstream of PKD during thymic selection is not clearly understood. PKD is activated by binding to DAG and, more importantly, by phosphorylation of serine residues in the activation loop (Ser707/711 in PKD2 and Ser731/735 in PKD3)3. In T cells, classical as well as ...
In previous studies, we found that mouse SHP-1 can block the progression of bacterial sepsis by inhibiting the NFκB signaling pathway (Wang et al., 2024). However, the potential anti-bacterial effects and regulatory mechanisms are still limited in teleost, especially in Chinese tongue sole (...
货号MA5-37377 Price (CNY) 2,662.00 下单后预计有货时间 02-Jun-2025 查看价格 批量或定制请求 Application Created with Sketch. 图:1/1 Phospho-SHP-1 (Tyr536) Antibody (MA5-37377) in Flow Flow cytometry of Phospho-Shp1 (Tyr536) using Ramos cells. Samples were incubated i...
货号A304-969A Price (CNY) 6,701.00 下单后预计有货时间 29-May-2025 查看价格 批量或定制请求 Application Created with Sketch. 图:1/1 PTPN6/SHP1 Antibody (A304-969A) in WB Detection of human PTPN6/SHP1 by western blot. Samples: Whole cell lysate (15 and 50 µg) from Jurkat cells ...