In The Lancet today, Willemien Nienhuis and colleagues1 describe a randomised trial of two antibiotic combinations for the treatment of Buruli ulcer in Ghana. The main finding, that the two quite similar regimens are equivalent, might seem unremarkable. However, this is an important study that ...
Amoxicillin is an antibiotic that may be used to treat infections caused by certain susceptible bacteria. Amoxicillin works by inhibiting the synthesis of bacterial cell wall mucopeptides (these are crystal lattice-like structures composed of amino acids that make up the cell wall). This weakens ...
Therapy can remain at seven days for patients with a documented ulcer. When using the 'test and treat' approach in patients with uninvestigated dyspepsia, the physician must assume that most patients will suffer from FD. In that clinical situation it is logical also to use prolonged antibiotic ...
CuringHelicobacter pyloriinfection in patients with ulcer disease improves their quality of life and decreases costs1. Regimens with the highest cure rates are also the most cost-effective2. Re-treatment after a failed earlier attempt is more difficult and expensive3. Therefore, physicians should try...
Severe vomiting and stomach pain kept him awake for nights. He shuddered to think of what it was like for patients who had such symptoms on and off for years. But by the time he started the antibiotic/bismuth treatment, his system had managed to eradicate the germ." "JBS Haldane, a ...
What are appropriate end-points for Helicobacter pylori eradication in the treatment of duodenal ulcer? The end-point of Helicobacter pylori eradication trials in peptic ulcer disease should be the presence or absence of continuing H. pylori infection, and no... MP Williams,RE Pounder - 《Drugs》...
Hence, even after surgical intervention, active management including fluid resuscitation, antibiotic therapy and the monitoring of clinical progress for potential deterioration or post-operative complications is required. However, empiric anti-fungal therapy is not routinely prescribed for patients with PPUs,...