They received relatively short courses of antibiotics with a median duration of 4 days. Only four of these patients became febrile during the followup period and there were no fatalities. Given the benign course of these patients, recommendations for prolonged antibiotic courses should be reconsidered...
Acute otitis media (AOM) is a common illness during childhood, for which antibiotics are frequently prescribed. Objectives To determine the effectiveness of a short course of antibiotics (less than seven days) in comparison to a long course of antibiotics (seven days or greater) for the treatment...
Therefore, the researchers randomly assigned 518 patients with complicated intra-abdominal infection and adequate source control to either the experimental group (n = 257) or the control group (n = 260). Patients in the experimental group received a fixed course of antibiotics for 4 ± 1 calendar...
we show that a shortened 5-day course of therapy wassuperiorto standard therapy because the short course achieved similar outcomes with fewer days of antibiotics," Derek Williams, MD, MPH, Vanderbilt University Medical Center, Nashville, Tennessee, toldMedscape...
hospital acquisition of infection, evidence of foci of tissue infection, presence of foreign material, immune status and response to antibiotics. These data support the following recommendations for the minimum duration of antibiotic treatment for carefully selected low-risk patients with bloodstream ...
All rights reserved. 展开 关键词: Adapted use of antibiotics Antibiotiques Antimicrobial therapy Bon usage Durée de traitement Multi-drug resistant organism Résistances bactériennes Treatment duration DOI: 10.1016/j.revmed.2015.12.003 年份: 2016 收藏 引用 批量引用 报错 分享 ...
The exclusion criteria were as follows: 1) immunocompromised patients; 2) presence of gram-negative bacteria found resistant to initial empiric antibiotics; 3) presence of deep-seated bacterial infections; 4) presence of concurrent infections and 5) 10 days). The clinical outcomes (i.e. mortality...
在临床安全且有证据支持的情况下,缩短抗生素治疗的疗程可减少抗生素暴露,从而降低细菌耐药性的产生,并降低发生抗生素不良事件的风险。而对于不同类型的感染,抗生素短期疗程和长期疗程的临床结果相似。“Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of...
So, you have decided that this well-appearing child can be diagnosed clinically based on his history and physical exam. You recall that there is an increasing amount of adult literature supporting short-courses of antibiotics for pneumonia.[[5]] Can you do this for our patient? What does the...
We enrolled adults (age ≥18 years) who met the US Centers for Disease Control and Prevention National Healthcare Safety Network criteria for VAP, had been mechanically ventilated for 48 h or longer, and were administered culture-directed antibiotics. In culture-negative cases, empirical antibiotic...