In recent years attention has rightly focused on trying to define which patients benefit from antibiotic treatment, and those in whom antibiotics can be avoided. The size ofRobertWilsonBMJThoraxWilson R. Short course of antibiotic treatment in acute exacer- bations of COPD. Thorax 2008;63:390-...
Acute otitis media (AOM) is a common illness during childhood, for which antibiotics are frequently prescribed. Objectives To determine the effectiveness of a short course of antibiotics (less than seven days) in comparison to a long course of antibiotics (seven days or greater) for the treatment...
Therefore, the researchers randomly assigned 518 patients with complicated intra-abdominal infection and adequate source control to either the experimental group (n = 257) or the control group (n = 260). Patients in the experimental group received a fixed course of antibiotics for 4 ± 1 calendar...
Methods/design Hypothesis Our hypothesis is that a two weeks short-course of intra- venous antibiotics in patients with IE caused by gram- positive cocci, without signs of persistent infection, is not inferior in safety and efficacy to conventional anti- biotic treatment (4–6 weeks). Aims The...
UPDATED November 27, 2014 // Six weeks of antibiotics may be sufficient for treating patients with diabetic foot osteomyelitis even in the absence of surgery, a new randomized prospective trial finds. The results from 40 patients seen at five French general hospitals between 2007 and 2009 were ...
在临床安全且有证据支持的情况下,缩短抗生素治疗的疗程可减少抗生素暴露,从而降低细菌耐药性的产生,并降低发生抗生素不良事件的风险。而对于不同类型的感染,抗生素短期疗程和长期疗程的临床结果相似。“Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of...
The use of prophylactic antibiotics to reduce post-cesarean section febrile morbidity has been advocated since 1968. Although this approach has theoretical and actual disadvantages, all but one study found a reduction in febrile morbidity when prophylactic antibiotics were used. An unresolved question ...
So, you have decided that this well-appearing child can be diagnosed clinically based on his history and physical exam. You recall that there is an increasing amount of adult literature supporting short-courses of antibiotics for pneumonia.[[5]] Can you do this for our patient? What does the...
Second, there is remarkable heterogeneity across studies in everything from antibiotic choice to duration of treatment to outcomes. Noronha et al. limited their analysis to studies where the same antibiotics were used in both arms, but across studies many different antibiotics were used. The half-...
"Several studies have shown shorter antibiotic courses to be non-inferior to the standard treatment strategy but in our study, we show that a shortened 5-day course of therapy wassuperiorto standard therapy because the short course achieved similar outcomes with fewer days of antibiotics," Derek ...