Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: an association of high acetate and low butyrate ratios with adenomatous polyps and colon cancer. Gut 1988; 29: 1539-1543Weaver GA, Krause JA, Miller TL, Wolin MJ. Short chain fatty acid distributions of ...
Short chain fatty acid (SCFA) enema therapy for treatment-resistant pouchitis following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) Patient-reported outcomes (PRO) convey important aspects of health status, complementing physician-reported measures. The PRO Measurement Information Syst...
Interest has been recently rekindled in short chain fatty acids (SCFAs) with the emergence of prebiotics and probiotics aimed at improving colonic and systemic health. Dietary carbohydrates, specifically resistant starches and dietary fiber, are substrates for fermentation that produce SCFAs, primarily ace...
Augenlicht et al., “Short-chain fatty acid metabolism, apoptosis, and Apc-initiated tumorigenesis in the mouse gastrointestinal mucosa,” (1999) Cancer Res. 59:6005-6009. Barbarat and Podevin, “Stoichiometry of the renal sodium-L-lactate cotransporter,” (1988) J. Biol. Chem. 263:12190...
13 Short‑chain fatty acids–microbiota crosstalk in the coronavirus disease (COVID‑19) 1201 has been reported for multiple conditions including ulcerative colitis, diversion colitis, radiation proctitis, and pouchitis, but later studies found no significant benefits to enema approach [60]...
Most of the carbohydrates of the fibre fraction are extensively broken down by the microflora when they reach the large intestine; this metabolic process results in the production of gas and short chain fatty acids (SCFA; essentially acetic, propionic and butyric acids). In non-ruminant mammals,...
Short-chain fatty acidsThermogels for enemaObjectives: The purpose of the study was to gel a rectal solution of short-chain fatty acids to decrease the loss of active materials in the colonic lumen and thereby optimize their absorption. Met......
The short chain fatty acid butyrate imprints an antimicrobial program in macrophages. Immunity. 2019;50:432-445.e7. https://doi.org/10.1016/J.IMMUNI.2018.12.018. Article CAS Google Scholar de Souza Vieira R, Castoldi A, Basso PJ, Hiyane MI, Saraiva Câmara NO, Almeida RR. Butyrate ...
Effects of Microbiota on Short Chain Fatty Acid Synthesis in the Gut Although numerous bacterial strains have been analyzed for their butyrate-producing capacities, Faecalibacterium prausnitzii (a member of Clostridium cluster IV) and Eubacterium rectale/Roseburia (Clostridium cluster XIVa) have currently ...
However, the pharmaceutical formulation of short-chain fatty acid supplements profoundly influences their delivery and absorption. Following an examination of SCFAs production, including acetate, propionate, and butyrate, within the intestinal milieu in the initial section of this review, the subsequent ...