9. The PD1/CTLA4 binder of claim 1, wherein the PD1/CTLA4 binder comprises a half-life extender which is a human serum albumin ISVD which comprises: CDR1 comprising the amino acid sequence GFTFSSFGMS (SEQ ID NO: 199) or SFGMS (amino acids 6-10 of SEQ ID NO: 199); CDR2 comprisi...