Coupling cell fate and dynamics, PrE cells form apical polarity-dependent actin protrusions required for RAC1-dependent migration towards the surface of the fluid cavity, where PrE cells are trapped due to decr
a, Schematic of experiments: POA and surrounding regions were dissected, nuclei extracted and snRNA-seq + snATAC-seq libraries prepared at eight developmental stages, two male and two female samples per age. E, embryonic; P, postnatal.b, Cell types with previously identified roles in social...
To ensure that our results are not due to outliers, we conducted Boxplot outlier analysis in SPSS for each dependent variable. Values > Q3 + 3(IQR) and values < 1Q − 3(IQR) were defined as outliers. Where outliers were detected, we conducted the analysis with and without th...
membrane tdTomato (mT, magenta) and scatter-plot of measured surface tension of outer cells versus logarithm ofPdgfraH2B-GFPfluorescence intensity of the cell. White arrowhead marks the site of cell aspiration and the white dotted line indicates cell surface contour.n = 40 cells from 24 ICM...
The adoption of agriculture triggered a rapid shift towards starch-rich diets in human populations1. Amylase genes facilitate starch digestion, and increased amylase copy number has been observed in some modern human populations with high-starch intake2,
The boxplots show the means (crosses), the median (horizontal bars) and inter-quartile range (boxes). The whiskers extend to the most extreme data point, which is no more than 1.5 times the IQR. Table 3. DLs and PSEs in unimodal and bimodal conditions for each experimental group. Mean...
Fig. 2. Boxplot of the data information for the training set and test set of both dataset tracks, including VOR of the complete skulls (top left), VOR of the implants (top right) and approximate defect area (bottom). 2. Experimental Design, Materials and Methods Cranial implant design is...
Overview of total antimicrobial resistance genes (ARGs) abundance per sample. Boxplots of the total ARGs in counts per million per sample, stratified by production system and sample type. Each sample is represented by a dot with horizontal jitter for visibility. The horizontal box lines represent...
Mechanistically, succinylation of the ligand of PD-1 (PD-L1) at lysine 129 led to its degradation. Increased carnitine palmitoyltransferase 1A (CPT1A), identified as a succinyltransferase for PD-L1, boosted anti-tumor activity. Preclinically, bezafibrate, a hyperlipidemia drug, upregulated CPT1A ...
. Gene expression levels were calculated using the ggboxplot function (in the ggpubr package in R). Each dot in the differentiation trajectories indicates a single cell. The combines violin and box plots ine–g(middle) show the data distribution and its probability density. In these box ...