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中文名称 : 含SH2结构域接头蛋白B抗体 别名 : bA3J10.2; OTTHUMP00000021397; RP11 3J10.8; RP113J10.8; SH2 domain containing adapter protein B; SH2 domain-containing adapter protein B; SHB (Src homology 2 domain containing) adaptor protein B; SHB adaptor protein (a Src homology 2 protein);...
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HSH2: a novel SH2 domain-containing adapter protein involved in tyrosine kinase signaling in hematopoietic cells. Biochem. Biophys. Res. Commun. 288: 1078 -1086.HSH2: A Novel SH2 Domain-Containing Adapter Protein Involved in Tyrosine Kinase Signaling in Hematopoietic Cells[J] . Tsukasa Oda,...
The Src homology 2 (SH2) domain-containing protein SH2-Bbeta binds to and is a substrate of the growth hormone (GH) and cytokine receptor-associated tyrosine kinase JAK2. SH2-Bbeta also binds, via its SH2 domain, to multiple activated growth factor receptor tyrosine kinases. We have pre...
SH2结构域2A(SH2 domain containing 2A,SH2D2A)基因编码的T细胞特异性衔接蛋白(T cell-specific adaptor protein,TSAD)是一种细胞内分子,具有免疫调节、免疫监视的功能。TSAD可结合淋巴细胞特异性蛋白酪氨酸激酶以引发信号,导致CD4 + T效应细胞产生细胞因子进行免疫调节 [ 1 ]。肿瘤方面,SH2D2A能够减少膀胱癌细胞...
Adapter Protein SH2B1β Cross-Links Actin Filaments and Regulates Actin Cytoskeleton The Src homology 2 (SH2) domain-containing adapter protein SH2B1beta plays a role in severe obesity, leptin and insulin resistance, and infertility. SH2B1b... L Rider,J Tao,S Snyder,... - 《Molecular Endocr...
Two partial cDNAs encoding novel SH2 domain-containing proteins were cloned and designated Shd and She. Both have homology to Shb, a previously reported SH2 domain-containing protein. Northern blot analysis showed that She is expressed in heart, lung, brain, and skeletal muscle, while expression...
SH2-B is a component of the signaling network involved in the regulation of cell shape and movement. SH2-B is related to the APS (adapter moleculecontaining PH and SH2 domains) family of adapter proteins, which character- istically contain a Pleckstrin homology (PH) domain, an SH2 domain...
关于Grb2的叙述正确的是()A.仅含SH2结构域B.属于鸟嘌呤核苷酸置换因子(GEF)C.为接头蛋白(adapterprotein)D.为单体G蛋白E.为GTP酶激活蛋