The Src homology 2 (SH2) domain-containing protein SH2-Bbeta binds to and is a substrate of the growth hormone (GH) and cytokine receptor-associated tyrosine kinase JAK2. SH2-Bbeta also binds, via its SH2 domain
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The Src homology-2 (SH2) domain-containing protein SH2-Bβ is a substrate of the growth hormone (GH) receptor-associated tyrosine kinase JAK2. Here we tested whether SH2-Bβ is involved in GH regulation of the actin cytoskeleton. Based on cell fractionation and confocal microscopy, we find...
中文名称 SH2 结构域蛋白C3抗体品牌 英文名称 Anti-SHC3 别名 N SHC; N-Shc; Neuronal Shc; NSHC; Protein Rai; Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SH
别名:SHC (phospho Tyr239 + Tyr240); SHC (phospho Y239 + Y240); p-SHC (Tyr239 + Tyr240); p-SHC (Y239 + Y240); p46; p52; p52 SHC; p52SHC; p66; p66 SHC; p66SHC; SH2 domain protein C1; SHC (Src homology 2 domain containing) transforming protein 1; SHC 1; SHC A; Shc...
Binding of the SH2 domain to the activation loop is required for STAT5AY694 phosphorylation by SFK, but at the same time promotes the persistent cytoplasmic localization of the transcription factor as found in BCR-ABL+ leukemia. As a consequence of the complex formation between tyrosine-...
Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1. J. Biol. Chem. 1999, 274, 19649–19654. [Google Scholar] [CrossRef] [PubMed] [Green Version] Nishida, K.; Wang, L.; Morii, E.; Park, S.J.; Narimatsu, M.;...
Src homology 3 domain-binding protein 2 (SH3BP2, also known as 3BP2) is an adapter protein expressed primarily in immune cells, such as myeloid cells [10,11], B cells [12,13], and T cells [14]. SH3BP2 regulates immune-cell functions by interacting with intracellular signaling protei...
79764 Fluorogenic PTP1B (Catalytic Region) Assay Kit 96 reactions bpsbioscience 79317 SHP-2 (catalytic domain) Homogeneous Assay Kit 96 reactions bpsbioscience PAP-6mg Papain 6mg brainbitsllc HA500 Hibernate A 500ml brainbitsllc TV-150 SM Tailveiner Restrainer for Mice smaller 1 1/8" id braint...
3A). We found that AR was enriched for SH2 domain-containing adaptor protein E-binding sites relative to the other receptors (p = 0.0377) but was depleted for sites that recruited most other domains (Fig. 3B). ErbB1, ErbB2, and ErbB3 were significantly enriched in phosphosites that ...