The human SH-SY5Y neuroblastoma cell-line expresses a functional P2X7 purinoceptor that modulates voltage-dependent Ca2+ channel function. J. Neurochem. 2002, 83, 285-298.Larsson K P, Hansen A J, Dissing S. The human SH-SY5Y neuroblastoma cell-line expresses a functional P2X7 purinoceptor that...
sh-sy5y Cells Organism Type Human A subline of the neuroblastoma SK-N-SH line derived from a metastatic bone tumor. Grows as a mixture of floating and adherent cells. Tissues Brain Phenotype Either Primary no Application Cell Culture / Growth Conditions,Protein Expression,Stable Cell Transfection,...
SH-SY5Y cells are a subclone of a neuroblastoma cell line derived from human bone marrow. With similar morphological, physiological, and biochemical characteristics to human cells, SH-SY5Y cells can be transformed into neuron-like cells, showing a ...
2）长散在核元件（Long Interspersed Nuclear Element, LINE-1）扩增实验：SH-SY5Y-BJ、SH-SY5Y-TJ、SH-SY5Y-WU及SH-SY5Y-HUST均可扩增出小鼠LINE-1所有片段，却无法扩增出人类的LINE-1。3）DNA测序：SH-SY5Y-BJ、SH-SY5Y-TJ、SH-SY5Y-WU及SH-SY5Y-HUST这四个样本的所有克隆均为小鼠DNA序列；SH-SY5Y-CS...
Designations: SH-SY5Y Depositors: JL Biedler Biosafety Level: 1 Shipped: frozen Medium & Serum: See Propagation Growth Properties: mixed, adherent and suspension Organism: Homo sapiens(human) Morphology: epithelial Source: Organ: brainDisease: neuroblastomaDerived from metastatic site: bone...
Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. PubMed: 6137586 特点和简介 据报道,该细胞的密度可高达1×106 cells/cm2,具有中等水平的多巴胺β羟化酶的活性。 ATCC CRL-2266(SH-SY5Y)人脑神经母细胞瘤接受后处理 1) 收...
3.J L Biedler et al., Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res. 1973 Nov;33(11):2643-52. 4.Jiang T et al., Identification of cross-contamination in SH-SY5Y cell line. Hum Cell. 2014 Oct;27(4):176-8. ...
In general, cells of human origin are attractive alternatives to the animal models for extrapolation of toxicity on humans. The characteristics, culture conditions and usefulness of the human neuroblastoma cell line SH-SY5Y as a model for axonopathy are presented in this chapter. It is described ...
SH-SY5YCytotoxicityOxidative stressApoptosisThe antioxidant, anti-inflammatory, and anticancer activities of Withania somnifera (WS) are known for a long time. This study was aimed to examine whether WS also diminishes 4-hydroxy-trans-2-nonenal (HNE)-induced neurotoxicity in human neuroblastoma (SH-...
The human neuroblastoma cell line, SH-SY5Y, is a commonly used cell line in studies related to neurotoxicity, oxidative stress, and neurodegenerative diseases. Although this cell line is often used as a cellular model for Parkinson’s disease, the relevance of this cellular model in the context...