A polypeptide-dimer comprising two soluble gp130 molecules, the molecules are fused to the Fc domain of an IgG1 protein, respectively, the hinge region of the Fc domain are suitable modified characteristics as provided in the dimer dimeric polypeptide that is is described. In a particularly ...
sgp130Fc dimers
Effect of soluble gp130-Fc (sgp130Fc) injection on the expression of S100A9 in colonic epithelial cells (CECs) from mice with dextran sulfate sodium (DSS)-induced colitis.Min Jeoung LeeJinKu LeeJi Won ChoiChangSeok Lee...
227Infarct size in a rat model of acute myocardial infarction is reduced by interleukin-6 trans-signalling blockade using sgp130fc but not an anti-il-6r mo... 227Infarct size in a rat model of acute myocardial infarction is reduced by interleukin-6 trans-signalling blockade using sgp130fc ...
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发现例如sgp130二聚体或sgp130Fc二聚体对治疗应用是有效的。 本发明潜在的技术问题是提供改善的sgp130Fc二聚体。 所述技术问题的解决通过提供权利要求中表征的实施方案而实现。在导致本发明的实验过程中,发现sgp130Fc融合蛋白的生物活性、可纯化性和稳定性显著地取决于sgp130和Fc部分之间的铰链区的氨基酸组成。将人...
真空绝热板(Vacuum Insulation Panel,VIP 板)是以微纤维玻璃棉为主要原材料,采用干法或湿法成网工艺制成的厚度为 1mm-10mm 的微纤维玻璃棉板。VIP板是一类具备导热系数低、体积小、质量轻、防火、环保无污染等特点的新型的高效绝热材料,在生产过程中VIP板不会采用消耗臭氧层物质(ODS)或是产生温室气体物质,能做到回...
随着中国经济的快速发展,减水剂行业也取得了可喜的发展,预计在2023年,中国减水剂行业的规模将进一步强化。减水剂行业主要通过使用减水剂,通过调节分子结构,改变物质的凝胶度,从而提高分散悬浮体从事工业生产活动和产品使用的性能及效果。 一、2023年中国减水剂行业销量分析 ...
丙烯酸丁酯-丙烯酸&正丁醇价差(元/吨),数据源于【研报】基础化工行业:下游需求回暖TDI、草甘膦、染料等涨价-20200905(17页).pdf。
A polypeptide-dimer comprising two soluble gp130 molecules, the molecules are fused to the Fc domain of an IgG1 protein, respectively, the hinge region of the Fc domain are suitable modified characteristics as provided in the dimer dimeric polypeptide that is is described. In a particularly ...