[17]. Filippas-Ntekouan S, Tsimihodimos V, Filippatos T, Dimitriou T, Elisaf M. SGLT-2 inhibitors: pharmacokinetics characteristics and effects on lipids. Expert Opin Drug Metab Toxicol. 2018 Nov;14(11):1113-1121. doi: 10.1080/17425255.2018.1541348. Epub 2018 Oct 31. PMID: 30360662. [...
8. Scheen AJ. Sodium-glucose cotransporter type 2 inhibitors for the treatment of type 2 diabetes mellitus[J]. Nat Rev Endocrinol, 2020, 16(10): 556-577. 9. 桑大森,吴寿岭,张旗.臂踝脉搏波传导速度与全因死亡的关系[J]....
具体而言,这些抑制剂包括卡格列净、达格列净和恩格列净,它们最初分别于 2013 年 3 月【US Food and Drug Administration. Highlights of Prescribing Information — Invokana】、2014 年 1 月【US Food and Drug Administration. Highlights...
要说起近几年最火的明星药物,少不了钠葡萄糖协同转运蛋白 2 抑制剂(SGLT2i),虽然它出道之时只是一款降糖药,但近年来国内外多项大型循证和指南加持,现在的 SGLT2i 已经凭借其独立于降糖外的心肾获益*成为了心血管和肾病领域的「当红炸子鸡」。SGLT2i 不仅是 2 型糖尿病(T2DM)合并动脉粥样硬化性心血管疾病...
Background Sodium glucose cotransporter-2 inhibitors (SGLT2i) reduce the risk of heart failure and new data show they can prevent atrial fibrillation (AF). We examined the association between SGLT2i and AF in the Food and Drug Administration adverse event reporting system (FAERS). Methods We ...
italia-or-perineum药物安全性更新/sglt2-抑制剂-reports-of-fournier-s-gangrene-necro https://www.gov.uk/drug-safety-update/sglt2-inhibitors-reports-of-fournier-s-gangrene-necrotising-fasciitis-of-the-genitalia-or-perineum生殖器或会阴筋膜炎.(2022年12月15日访问)Napp Pharmaceutical Limited,2013年11月...
[17]. Filippas-Ntekouan S, Tsimihodimos V, Filippatos T, Dimitriou T, Elisaf M. SGLT-2 inhibitors: pharmacokinetics characteristics and effects on lipids. Expert Opin Drug Metab Toxicol. 2018 Nov;14(11):1113-1121. doi: 10.1080/17425255.2018.1541348. Epub 2018 Oct 31. PMID: 30360662. ...
要说起近几年最火的明星药物,少不了钠葡萄糖协同转运蛋白 2 抑制剂(SGLT2i),虽然它出道之时只是一款降糖药,但近年来国内外多项大型循证和指南加持,现在的 SGLT2i 已经凭借其独立于降糖外的心肾获益*成为了心血管和肾病领域的「当红炸子鸡」。SGLT2i 不仅是 2 型糖尿病(T2DM)合并动脉粥样硬化性心血管疾病...
Sodium-glucose linked transporter 2 (SGLT2) inhibitorsType-2 diabetes mellitus (T2DM)DNA double-strand breaks (DSBs) are involved in many cellular mechanisms, including replication, transcription, and genome rearrangements. The recent observation that hot spots of DSBs in human chromosomes delimit DNA...
SGLT2 inhibitors, DPP-IV inhibitors, pharmaceutical compositions comprising an anti-diabetic drug by further necessary and uses thereofThe invention relates to a pharmaceutical composition according to the claim 1 comprising an SGLT2 inhibitor, a DPPIV inhibitor and a third antidiabetic agent which is...