[6]Nuffield Department of Population Health Renal Studies Group; SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcome...
[6]Nuffield Department of Population Health Renal Studies Group; SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collabor...
具体而言,共识推荐了SGLT2i在CKD早期(G1~G3a)和晚期(G3b~G5)的应用;明确指出用药前需全面评估风险,包括血容量不足、低血压、酮症酸中毒、泌尿生殖道感染等;并提出了与其他降糖药、降压药、利尿剂等药物的联合使用策略;且详尽指导了用药期间如何监测和处理可能的不良反应,同时反复强调了对CKD患者加强宣教的重要...
[1]Milder TY,Stocker SL,Abdel Shaheed C,et al.Combination therapy with an SGLT2 inhibitor as initial treatment for type 2 diabetes:a systematic review and meta-analysis[J].J Clin Med.2019,8(1):45.DOI:10.3390/jcm8010045. [2]Guillausseau PJ.Influence of oral antidiabetic drugs compliance ...
[4]. Nuffield Department of Population Health Renal Studies Group, SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo- controlled trials[J]....
[11] Shiba, K., Tsuchiya, K., Komiya, C., et al.(2018). Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH, Sci Rep 8, 2362.https://doi.org/10.1038/s41598-018-19658-7 ...
[1]Milder TY,Stocker SL,Abdel Shaheed C,et al.Combination therapy with an SGLT2 inhibitor as initial treatment for type 2 diabetes:a systematic review and meta-analysis[J].J Clin Med.2019,8(1):45.DOI:10.3390/jcm8010045. [2]Guillausseau PJ.Influence of oral antidiabetic drugs compliance ...
5. Lin B, et al. Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice. Cardiovasc Diabetol. 2014; 13: 148. 6. Hierro-Bujalance C, et al. Empagliflozin reduces vascular damage and co...
[12].Jongs N, Chertow GM, Greene T, et al. Correlates and Consequences of an Acute Change in eGFR in Response to the SGLT2 Inhibitor Dapagliflozin in Patients with CKD. J Am Soc Nephrol. 2022;33(11):2094-2107. 声明:本文的采访/撰稿/发布由阿斯利康提供支持。仅供医疗卫生专业人士参考,不得...
来源：[1]Sodium glucose co-transporter 2 inhibitors in heart failure with preserved ejection fraction: a systematic review and meta-analysis. Eur J Prev Cardiol, 1 Dec 2021 [2]The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial. Nature...