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Circulation144, 4-6, doi:10.1161/CIRCULATIONAHA.121.054442 (2021). 8. Inoue, T. et al. Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation.Eur. J. Pharmacol.806, 25-31, doi:10.1016/j.ejphar.2017.04.010 (2017). 9. Niu, Y....
"Sotagliflozin" is the first oral SGLT1 inhibitor developed to treat adult patients with T1DM in combination with insulin, which is to be reviewed by the FDA. Studies have shown that people with T1DM who take sotagliflozin in addition to optimized insulin therapy have lowerhemoglobin A1clevels ...
Key words:sotagliflozinSGLT2SGLT1inhibitordiabetes 1药物概况 通用名:sotagliflozin 别名:LX4211 化学名:(2S,3R,4R,5S,6R)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(甲硫基)四氢-2H-吡喃-3,4,5-三醇 CAS:1018899-04-1 分子式:C21H25ClO5S ...
英文名: SGLT inhibitor-1 英文别名: SGLT inhibitor-1;SGLT inhibitor 1,SGLT inhibitor1;D-Glucitol, 1,5-anhydro-4-deoxy-1-C-[7-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-2,3-dihydro-4-methoxy-5-benzofuranyl]-4-fluoro-, (1S)- 中文名: SGLT inhibitor-1 中文别名: 化合物 T12893...
SGLT inhibitor-1 是一种高效的钠葡萄糖共转运蛋白 (SGLTs) 双重抑制剂,针对人类SGLT1和hSGLT2具有较强的选择性,其半抑制浓度 (IC50) 分别为43 nM和9 nM。
MCE 站:SGLT inhibitor-1 产品活性:SGLT inhibitor-1 是一种有效的钠葡萄糖协同转运蛋白 (SGLTs) 双抑制剂,抑制 hSGLT1 和 hSGLT2 的 IC50 分别为 43?nM 和 9?nM。 研究领域:Membrane Transporter/Ion Channel 作用靶点:SGLT 相关产品:Empagliflozin | Phlorizin | Phloretin | Canagliflozin hemihydrate | Tr...
As SGLT1 inhibitor 4-isopropyl phenyl-glucitol compoundBy no tendency of the present invention relates body retention properties, inhibit SGLT1 activity, suppress absorption of glucose and the like in the small intestine, suppress (impaired glucose tolerance) or postprandial hyperglycemia, so that, ...
SGLT inhibitor-1 | MedChemExpress(MCE) 英文名称: 总访问: 69 国产/进口: 进口 半年访问: 5 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 电询 最后更新: 2024-11-4 货号: HY-112807 CAS 号: 2247314-23-2 参考报价: 电询 立即询价 电话咨询 ...