提供的SFPQ人源重组蛋白(Q01)产品为带有GST标签的人源SFPQ部分序列重组蛋白,其对应的GeneID号为6421。 产品描述 与其它公司提供的重组蛋白不同,该SFPQ人源重组蛋白(Q01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻译后修饰...
基因名: SFPQ 别名: PSF,POMP100,PPP1R140 基因ID: 6421 Chromosome:(GRCh37) 1 Start: 35641981 End: 35658766 Strand: 信号通路: SFPQ 基因突变与药物关于我们 “基因医生”项目,可以为肿瘤患者提供全流程逐级的治疗方案与治疗手段。本项目创始科学家团队在基础医学研究领域拥有丰厚实战经验,以NGS及RNA-SEQ...
PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers: clinicopathologic, immunohistochemical, and molecular characteristics suggesting classification as a distinct entity. Am J Surg Pathol...
保存条件 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. 背景资料 Splicing factor,proline- and glutamine-rich is a protein that in humans is encoded by the SFPQ gene.Enables DNA binding activity;histone deacetylase ...
Sfpq promotes post-transcriptional silencing mediated by miRNAs in both nucleoplasm and cytoplasm.aGene expression differences in let-7a-transfected P19 cells upon Sfpq knockdown and control. Differential expression is plotted for mRNAs containing canonical let-7a-binding sites (BS) localized in the 3...
Gene Name SFPQ Accession No. P23246 Alternate Names 100 kDa DNA pairing protein; 100 kDa DNA-pairing protein; 100 kDa subunit; DNA binding p52/p100 complex 100 kDa subunit; DNA-binding p52/p100 complex; hPOMp100; Polypyrimidine tract binding protein associated splicing factor; Polypyrimidine tract...
Followed by transfection with siRNA targeting SFPQ gene in BEL-7402 cell line,cell prolifera-tion,cell migration and cell invasion and EM T related proteins were detected by CCK 8,transwell and western blot assays,respectively. Results IHC score in tumor tissues was significantly higher th...
SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear ...
DBHS proteins are frequently identified engaging in almost every step of gene regulation, including but not limited to, transcriptional regulation, RNA processing and transport, and DNA repair. Herein, we present a coherent picture of DBHS proteins, integrating recent structural insights on dimerization...
Entrez GeneID 6421 Swissprot P23246 WB Predicted band size Calculated MW: 76 kDa; Observed MW: 100 kDa Host/Isotype Rabbit IgG Antibody Type Primary antibody Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity Human,...