The present invention relates to the field of separating chiral isomers from one another. In particular, the invention relates to the field of separating chroman or chromene compounds, in particular tocopherol, 3,4-dehydro-tocopherol, and tocotrienols, as well as their protected forms of chiral ...
By Chiral Technologies, Inc. Article Sponsored Content - EUThis application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and Hydrobenzoin as a test compound.Recent Videos ...
Accessing the power of normal-phase chromatography with the ease and reliability of reversed-phase chromatography is critical for separation scientists like you doing Supercritical Fluid Chromatography (SFC) applications. With the Torus, Trefoil, and Viridis SFC Column chemistries and Waters SFC ...
4. R.W. Stringham, Chiral Separation of Amines in Subcritical Fluid Chromatography Using Polysaccharide Stationary Phases and Acidic Additives, J. Chromatogr. A 1070 (2005) 163–170. 5. Achiral Supercritical Fluid Chromatography (SFC) for the Purification of Pharmaceuticals by Thomas Wolf, Aldo Mei...
Figure 13 shows the chiral separation of the enantiomers and diastereomers of permethrin using both normal-phase HPLC and SFC. All four peaks could not be resolved using HPLC; however they were resolved in less time and using a shorter column using SFC....
3.5?Conclusion Supercritical fluid chromatography (SFC) is emerging as a popular technology in the industry for the separation and purification of a variety of compounds from complex matrices. Improvement in the instrumentation and development of chiral stationary phases has made SFC an attractive ...
One of the biggest challenges is finding the best column for separating compounds of various types, as there is no universal chiral stationary phase, and predicting which chiral stationary phase will provide the best separation is difficult. Often, more than one column may provide some separation,...
HPLC is the most widely used method for the separation and determination of enantiomers. It is especially suitable for the analysis of chiral materials with strong polarity and poor thermal stability. Supercritical fluid chromatography (SFC) is a new chromatographic technique. Because it has the advan...
Using this system in RPLCmode, achiral separation of warfarin and its five hydroxylated metaboliteswas performed. While in SFC mode, both chiral and achiral separations wereperformed. The chiral SFC separation method was validated for selectivity,resolution, precision, limit of detection (LOD), and ...
McCauley, Chiral Purification of Volatile Flavors and Fragrances by SFC, Application Note, August 2014, 720005150EN. v. C.J. Hudalla, A. Tarafder, J. Jablonski, R. Roshchin, K. Fountain, M. Patel, M. Hardink. w.如需更多有關實用應用手冊和參考資料的資訊,請造訪www.waters.com,並在搜...