Loss of function (LoF) mutations (stop-gained or out-of-frame insertions/deletions leading to a stop-gained mutation) were classified as severe since these almost universally eradicate ARSA enzyme activity (an exception might be a terminal, stop-gained mutation) [13]. In this way, we ...
Furthermore, based on the severity of CAD, the CAD group was subdivided into the single-vessel (n = 144) and multi-vessel (n = 287) CAD groups. Fig. 1 Flow chart of subject recruitment. CAG coronary angiography, CAD coronary artery disease; BMI, body mass index; FBG, fasting...
MECP2maps to chromosome Xq28, includes four exons, and encodes the methyl CpG binding protein 2 (MECP2) (NM_004992.4). The protein fine tunes the expression of thousands of genes in the brain by binding to methylated cytosines predominantly in the CG and CAC context [1,2,3]. Loss-of-...
In some cases, inflammation of the facial nerve spreads to the vestibulocochlear nerve, causing dizziness or hearing disturbance [2]. However, despite facial palsy caused by VZV infection, vesicular lesions may not appear on the ears or may occur a few days after facial palsy, which delays the...
Table 1. Traffic crashes data of older pedestrians. 4. Methodology Based on the data procession, the method flow chart of this study is proposed and is shown in Figure 6. Figure 6. Method flow chart. This study is modeled using XGBoost. Additionally, SHAP is used to interpret the XGBoo...