sepsisseptic shockEpidemiological studies document that males are more prone than females to develop severe sepsis and this is confirmed by Sakr and colleagues in the previous issue of Critical Care. However, the impact of gender on prognosis of severe sepsis is a matter of debate. Sakr and ...
INTRODUCTION: Whether diabetes mellitus increases the risk of acute kidney injury (AKI) during sepsis is controversial. MATERIALS AND METHODS: We used a case-control design to compare the frequency of AKI, use of renal replacement therapy (RRT), and renal recovery in patients who had severe seps...
Thus, we aimed to identify predicting factors for severe sepsis and assess the outcome of fluid resuscitation of such children. In this retrospective case-control study SAM children aged 0–59 months, admitted to the Intensive Care Unit (ICU) of the Dhaka Hospital of the International Centre ...
Thus, patients who did not develop severe sepsis and who had no functional limitations prior to their hospitalization developed an average of 0.48 (95% CI, 0.39-0.57; n = 2852; P for difference vs sepsis < .001, eTable 3) new functional limitations. Patients with mild to moderate ...
www.nature.com/scientificreports OPEN Clinical outcomes of severe sepsis and septic shock patients with left ventricular dysfunction undergoing continuous renal replacement therapy Guangwei Yu 1,6, Kun Cheng2,3,5, Qing Liu1, Wenwei Wu1, Huashan Hong4,6* & Xiaohong Lin...
Different responses among the sexes are increasingly recognized as a major factor in the outcome of patients with trauma and sepsis. In the past years, several animal studies revealed that females had advantageous immunologic and cardiovascular responses during infectious challenges.1, 2, 3 In addition...
Objective A study was undertaken to characterise how doctors in emergency medicine (EM), acute medicine (AM) and critical care (ICU) in the UK, USA and Australia and New Zealand (ANZ) approach the initial resuscitative care of patients with severe sepsis. Methods In 2007, members on the ...
Microcirculatory alterations were less severe in the later than in the earlier (proportion of perfused small vessels, 74 [57-82]% vs. 63 [48-71]%, p = 0.004) phase of sepsis. In multivariable analysis focused on the early period of sepsis, proportion of perfused small vessels and lactate...
This cohort study evaluates the association of implementation of the Severe Sepsis and Septic Shock Early Management Bundle (SEP-1) with sepsis treatment
The presence of circulating endotoxin is common during sepsis but its prognostic value is poor. We hypothesized that this lack of correlation with outcome could be related in part to the presence of circulating antiendotoxin antibodies. In a 14-bed medical intensive care unit, in an 821-bed ter...