The definition of sepsis is two or more systemic inflammatory response criteria plus a known or suspected infection. Severe sepsis is sepsis with acute organ dysfunction. Acute organ dysfunction can manifest in any organ, and frequently manifests clinically as shock, respiratory failure, acute kidney...
Severe sepsis in community-acquired pneumonia: when does it happen, and do systemic inflammatory response syndrome criteria help predict course? Chest 2006; 129:968-78.Severe sepsis in community-acquired pneumonia;when does it happen,and do systemic inflammatory response syndrome criteria...
We included all RCTs comparing EGDT with UC or LGT in patients with severe sepsis or septic shock. Exclusion criteria The exclusion criteria were as follows: (1) studies with duplicated data; (2) non-randomized studies; (3) meta-analyses, animal studies, studies of non-adult populations, or...
THE CRITERIA FOR DIAGNOSIS AND RISK FACTORS IN TRIGGERING MULTIPLE ORGAN DYSFUNCTION WITH SEVERE SURGICAL SEPSISSEVERE SURGICAL SEPSISMULTIPLE ORGAN DYSFUNCTIONSIRSRISK FACTORSStudy is based on analysis of the dysfunction of visceral and systemic structure in relation to the location of the outbreak in ...
A total of 1892 adult patients with severe sepsis and septic shock were initially screened and 629 patients had echocardiograms performed. Among 227 patients who met the inclusion criteria with LV dysfunction, 132 patients received CRRT. Thirty- seven, 71 and 24 patients had LVSD, LVDD, and ...
sepsis: 1) hypotension caused by sepsis; 2) lactic acid levels higher than the normal value; 3) although given enough fluid resuscitation, urine volume remains <0.5 ml/kg/h for at least 2 hours; 4) non-pneumonic acute lung injury and PaO2/FiO2 <200 mmHg; 5) pneumonic acute ...
Sepsis Guidelines, fluid resuscitation to achieve a CVP of 8-12 mmHg is one of the key recommendations [2]. Optimizing the fluid status of patients with severe malaria also has appeal as this group has a reduced effective circulating volume [9–11] and lactic acidosis and renal impairment -...
The prospectively defined severity criteria were: a peripheral venous base deficit of > 6 mmol/L, a blood urea nitrogen > 60 mg/dL (21.4 mmol/L) or pulmonary oedema (defined as oxygen saturation < 90% on room air with bi-basal crepitations on respiratory examination). These inclusion ...
was performed. Patients were stratified according to the receipt of tocilizumab for cytokine storm and matched to controls using propensity scores. The primary outcome was in-hospital mortality. A total of 274 patients meeting inclusion and exclusion criteria were identified and 132 patients were includ...
This makes it quite difficult to create a standard clinical definition of sepsis. This lack of definitive criteria for a diagnosis of sepsis makes it easily misdiagnosed, and consequently improperly treated. If, however, a diagnosis of sepsis is made, it is often still made late and treatment ...