Nolan P.K., D.C., Long F., Dishop M.K., Baker P., Guarin M., Allen E.D., Rennenbohm R., Severe diffusion capacity reduction in a case of systemic onset juvenile rheumatoid arthritis with mild pulmonary hypertension. Chest, 2005. 128(4): p. 435S-436S....
Reduction in the diffusion capacity of the lung for carbon monoxide (DLCO) is the most common functional consequence of severe SARS-CoV-2, occurring typically during the acute phase12 and persisting up to six months post-recovery in up to 50% of Covid-19 survivors7,13. Alongside respiratory...
Analysis of patient-derived cells demonstrated a significant reduction in TBX4 expression resulting from this intronic variant. Our study illustrates the variable expressivity in cardiopulmonary phenotype conferred by TBX4 mutation and the utility of genetic diagnostics in enabling accurate identification and...
Despite normal pulmonary function testing, normal exercise capacity, and a minority of patients (18%) with a clinically important reduction in distance walked in 6 minutes, many patients continued to report shortness of breath and fatigue as notable contributors to exercise limitation at 1 year. ...
2), that restrict the passage of small solutes and allow for mainly the diffusion of carbon dioxide and oxygen [1,65]. Further, type I and type II alveolar cells have additional capacity to absorb excess alveolar fluid via ion transport channels, with further fluid resorption into the lung ...
Clarithromycin is also effective for the treatment of acute episodes of bronchospasm in children with a history of recurrent wheezing.16 A randomized, double blind placebo controlled trial on 55 asthmatic patients reported a significant reduction in TNF-alpha, IL-5, and IL-12 levels in the ...
thymic method can reduce the side effects of antibiotics and other drugs and long-term MV on the body, and on the other hand, the reduction of medication, hospital stay, and MV time actually reduces the economic burden of patients and their families, which is conducive to improving pharmacoec...
(83.2% vs. 63.1%;p< 0.001). The same applied to the FVC% predicted (80% in responders vs. 62% in non-responders;p< 0.001). The responders demonstrated a higher diffusion capacity on admission compared to the non-responders (DLCO% predicted 62% in responders vs. 47% in non-responders...
With a further reduction in the grain size below 70 nm, the negative deviations appear, and the increase in the strength becomes less significant. 3.4. Iron The Hall–Petch plot for iron is shown in Figure 4. Despite some deviations, the datum points fall close to the Hall–Petch ...
Micro- and nanoplastics can interact with various biologically active compounds forming aggregates of which the effects have yet to be understood. To this end, it is vital to characterize these aggregates of key compounds and micro- and nanoplastics. In