Chew, AL, Bennett, A, Smith, CH, Barker, J and Kirkham, B (2004). Successful treatment of severe psoriasis and psoriatic arthritis with adalimumab. Br J Dermatol 151: 492-496.Chew,AL,Bennett,A,Smith,CH,Barker,J,Kirkham,B.Successful treatment of severe p...
Psoriasis is a chronic, genetically determined, immunomediated, inflammatory skin disease affecting approximately 2 - 3% of the Caucasian population. Systemic treatment is required in moderate to severe plaque-type psoriasis forms or psoriatic arthritis. However, cumulative organ toxicity, lack of efficacy...
A temperature of approximately 39 †C was sought. The psoriasis would often go into remission for several months. This therapy also helped psoriatic arthritis. First Page Preview View Large Full Text Download PDF Full Text Cite This Permissions Access through your institution JAMA+ AI ...
Three specific tumor necrosis factor (TNF) antagonists, adalimumab, etanercept and infliximab, have been approved for the treatment of psoriasis. Their efficacy, not only in psoriasis but also in psoriatic arthritis, has been demonstrated in large prospective randomized placebo-controlled trials. At pre...
Women observed to have significantly lower Psoriasis Area Severity Index scores than men. A majority of autoimmune diseases, such as systemic lupus erythematosus, multiple sclerosis, and rheumatoid arthritis, are more common among women than men. It has long been speculated that men may face a ...
Low prescription rate for systemic treatments in the management of severe psoriasis vulgaris and psoriatic arthritis in dermatological practices in Berlin and Brandenburg, Germany: results from a patient registryLow prescription rate for systemic treatments in the management of severe psoriasis vulgaris and...
BACKGROUND: Secukinumab, a fully human monoclonal antibody that selectively neutralizes IL-17A, has been shown to have significant efficacy and a favorable safety profile in the treatment of moderate to severe psoriasis and psoriatic arthritis. OBJECTIVE: To assess the efficacy and safety of secukinum...
Patient perspectives in the management of psoriasis: results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey. J Am Acad Dermatol. 2014;70(5):871-881.e871-830.Google ScholarCrossref 2. Parisi R, Symmons DP, Griffiths CE, Ashcroft DM...
Severe psoriasis is a systemic disease with significant co-morbidities, such as psoriatic arthritis and met- abolic syndrome2. In recent years, biological therapies including anti-tumor necrosis factor (TNF)-α treatment have greatly increased therapeutic choices for patients with severe psoriasis. ...
In 100 consecutive patients admitted to the hospital for control of severe psoriasis, 25 had radiologic changes characteristic of psoriatic arthritis. Twenty had erosions and mild sclerosis around the sacroiliac joint; in eight of these, asymptomatic sacroiliac changes were the sole manifestation of mus...