但是这些基因突变对MDS病理生理学以及向AML转化的影响机制需进一步深入研究。 SET domain-containing 2(SETD2)是主要的哺乳动物组蛋白甲基转移酶,可以催化组蛋白3上第36位赖氨酸的三甲基化(H3K36me3)。2005年,孙晓建等人首次发现一种新...
Get V-set domain containing information, such as approved symbols, names and synonyms. Sino Biological develops proteins, antibodies, genes, ELISA kits and other research reagents for V-set domain containing, and all are produced in house.
SETD2代表的是SET domain containing 2。当然,这是一个奇怪的名字,直译是“第2个含有SET这个东东的东东”。。。 可见最早发现这个基因(或蛋白质)的人内心是多么绝望——发现是有了,但它是做啥的啊!!!俺怎么发大文章啊!!! 当然我们不需要消耗自己的脑细胞去思考这个问题。SETD2基因编码的SETD2蛋白,是一种...
The SET domain-containing genes have been identified and functionally characterised for their roles in growth, development, and stress responses in several plant species, includingArabidopsis thaliana[21],Camellia sinensis[22],Gossypium raimondii[23], Malus domestica[24], Oryza sativa[25],Populus tricho...
Whereas Rph1 and KDM4A are considered as erasers for the H3K36me3 mark, yeast Set2 (SET domain-containing 2) and its mammalian homolog counterpart SETD2/KMT3A/HYPB (SET domain containing 2, histone lysine methyltransferase) are considered to be the writers responsible for this histone post...
is flanked by a set of variable regions, pre-SET (or n-SET), i-SET and post-SET (or c-SET), which are inserted immediately N-terminally within the SET domain or immediately C-terminally outside of the SET domain (Fig.1). An unusual feature of SET domain-containing methyltransferases ...
According to the results mentioned above, one of the most differentially expressed circRNAs, circSETD3 (hsa_circ_0000567), which is derived from exons 2–6 of the SET domain-containing 3 (SETD3) gene, was selected for further investigation. Its genomic structure is shown in Figure 3A. The...
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For IPs and URLs that need to be unblocked on your firewall, see Allowed IP addresses and domain URLs.Why does my scale set agent configuration script call Add-MpPreference and configure Windows Defender on the agent?To improve performance and reliability, the configuration scripts call Add-...
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