Background Ketones, including beta hydroxybutyrate (BHB), are produced in conditions of negative energy balance and decreased glucose utilization. Serum BHB concentrations in cats are poorly characterized in diseases other than diabetes mellitus. Hypothesis Serum BHB concentrations will be increased in ...
Beta-Hydroxybutyrate or Ketonesare produced by the liver when the body is fasting or going through prolonged exercise. Ketones use the fat in the body to produce fuel for energy. Ketone bodies are able to create much greater amounts of energy than glucose which is the bodies primary fuel sour...
The body mass index (BMI), percent body fat (% body fat), and serum leptin, insulin, cortisol, glucose, beta-hydroxybutyrate (BOHB), and nonesterified fatty acids (NEFA) were determined in 11 men and 13 women (age, 20 to 41 years, BMI, 21.2 to 26.8 kg/m2) before and during 7 ...
(2009) Ablation of ARNT/HIF1beta in liver alters gluconeogenesis, lipogenic gene expression, and serum ketones. Cell Metab 9: 428-439.Wang XL, Suzuki R, Lee K, Tran T, Gunton JE, Saha AK, Patti M-E, Goldfine A, Ruderman NB, Gonzalez FJ, Kahn CR: Ablation of ARNT/HIF1β in ...
Furthermore, bilirubin nanoparticles induce hepatic fat utilization, increase plasma ketones, and reduce hepatic steatosis [77]. In addition to bilirubin’s direct action as a PPAR-α ligand, bilirubin acts via FABP1, CAR, and LXRs [68]. CAR has recently been identified as a therapeutic target...
The ketogenic diet (KD) has been successfully used to treat pediatric refractory epilepsy since the 1920s and is currently being investigated as an adjunct treatment for many disease states. The therapeutic efficacy of the KD results from an elevation of blood ketones. We previously reported that ...