This prospective study was done to determine the normal range of serum alanine aminotransferase (ALT) in healthy normal population of Yazd from October 2008 to June 2009. Methods: In this study, 565 randomly selected apparently healthy people without any defined diseases were selected .Cases who ...
Olympus Corporation, Tokyo, Japan), and the upper limit of normal (ULN) ALT was defined as 50 IU/L for men and 38 IU/L for women. Serum HBsAg concentration was quantitatively assessed using Elecsys® HBsAg II Quant Assay (Roche Diagnostics, Penzberg, Germany), with a dynamic range ...
With the exception of a few subjects, the level of liver and kid- ney biomarkers were in the normal range, indicating that subject did not have any liver or kidney injuries. We found that the levels of total bilirubin were positively correlated with the adduct level. Moreover, subjects with...
Anti-HBs was detected in 21 (64%) of the 33 patients with HBsAg clearance at median time of 15 months (range 0–26) after HBsAg loss and median titer 102 mIU/mL (range 12–943). All pgRNA positive samples had qHBsAg > 100 IU/mL, but no significant difference between pgRNA ...
Even for HCC versus Recovery patients within the normal range of AFP, FN1 had an AUROC value of 0.779, compared with 0.544 for AFP (Fig. 4D). This 2-marker panel had an AUROC value of 0.821. Thus, we concluded that FN1 complemented AFP when these 2 markers were combined to ...
Healthy control persons as the HC group were used for assessing the upper limit of normal. Abbreviations: HC, healthy control; Sens, sensitivity; Spec, specificity; PPV, positive predictive value; NPV, negative predictive value; DOC, dithiothreitol-oxidizing capacity Full size image Comparison of ...
The detectable range was 0.12 to 75pmol/L FT4 in serum. The mean coefficients of variation within and between assays were 1.7%-4.4% and 3.2%-9.1%, respectively. The non-specific binding was less than 1%. This new assay was compared with a commercial radioimmunoassay kit for FT4 (labelled ...
Serum sPD1 levels were greater in CHB than in controls and positively correlated with levels of ALT, AST, total bilirubin, HBV DNA, AST to platelet ratio index ((AST/upper limit of the normal AST range) X 100/platelet count), fibrosis score Fib4, hepatic inflammatory score and fibrosis bu...
The cells suppressed T-cell proliferation, displayed normal karyotype and typical MSC differentiation potential and phenotype. The BM-MSCs were, however, consistently HLA-DR positive when cultured in platelet lysate (7.5–66.1 %). We additionally show that culture media antibiotics and sterile ...
Mean ALT levels, though still within the normal range was significantly (p<0.05) higher for the HBsAg sero-positive group compared with the control group. Result of this study suggests the need to curb the spread of HBV and hence its possible progression to more chronic liver diseases such ...