Also Known As: Free Light Chains, SFLC, FLC, Kappa and Lambda Free Light Chains, Quantitative Serum Free Light Chains with Ratio Board Approved At a Glance Why Get Tested? To help detect, diagnose, and monitor plasma cell disorders (dyscrasias) such as multiple myeloma, primary amyloidosis,...
Conclusion: Serum-free light chains should be requested when there is a high index of clinical suspicion. Neither SFLC nor SPE should be performed in isolation when screening patients for monoclonal gammopathy, to ensure that no patient is missed. What this study adds: The s...
Serum free light chains: an alternative to the urine Bence Jones proteins screening test for monoclonal gammopathies. Clin Chem. 2006;52(9):1743–8. Article CAS PubMed Google Scholar Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, et al. International Myeloma Working ...
Ressources | Current Status of Detecting Monoclonal Antibodies and Free Light Chains in Serum | Deutschland
Serum Free Light Chains in the Diagnosis and Monitoring of Patients with Plasma Cell Dyscrasias Serum free light chain assay is a recently available test for diagnosis and monitoring of patients with plasma cell dyscrasias. In particular, this test is especially useful in patients that were previousl...
Serum Free Light Chains in the Diagnosis and Monitoring of Patients with Plasma Cell Dyscrasias Serum free light chain assay is a recently available test for diagnosis and monitoring of patients with plasma cell dyscrasias. In particular, this test is especially useful in patients that were previousl...
Early reduction of serum-free light chains associates with renal recovery in myeloma kidney. J Am Soc Nephrol. 2011;22(6):1129–36. Article PubMed PubMed Central CAS Google Scholar Jain P, Calvert M, Cockwell P, McManus RJ. The need for improved identification and accurate classification ...
Immunoglobulin free light chains (FLCs) are normally produced by B cells in slight excess to provide the correct assembly of intact immunoglobulins. However, only 60% of FLCs assemble correctly into newly synthesized immunoglobulins, while the rest are released into the bloodstream giving rise to ...
Abstract 18079: Targeted Use of Serum Free Light Chain Assay in the Diagnosis of Light Chain Amyloidosis in Patients With Heart Failure The serum immunoglobulin-free light chain (FLC) assay measures levels of free 魏 and 位 immunoglobulin light chains and is an invaluable tool in the evalua......
FULL PAPER British Journal of Cancer (2014) 110, 2277–2282 | doi: 10.1038/bjc.2014.121 Keywords: hepatocellular carcinoma; free light chains; albumin; biomarker; serum; proteomic; alpha-fetoprotein Diagnostic and mechanistic implications of serum free light chains, albumin and alpha-fetoprotein in ...