Sertoli cells are involved in this process. Glutathione (GSH), produced by Sertoli cells, has an essential role in cell protection against oxidative stress. Intracellular GSH content is maintained by de novo synthesis, involving glutamate-cysteine ligase catalytic (GCLC) and modulatory (GCLM) ...
Sertoli cells are also involved in migration of differentiating germ cells towards the tubular lumen. This movement leads to a continuous remodeling of the plasma membrane and requires synthesis of several proteases, including urokinase, tissue-type plasminogen activator, cyclic protein 2, collagenase IV...
Sertoli cells are involved in :- View Solution Assertion Sertoli cells are being involved in the process of spermatogenesis. Reason Nutrition of developing sperms is provided by Sertoli cells. View Solution Sertoli cells are nourishing cells in the testis. These also secrete a hormone. Identify ...
The data suggest that one or more of these polypeptides are directly involved in the adhesion of germ cells to Sertoli cell monolayers in vitro.doi:10.1002/j.1939-4640.1992.tb01651.xSEAN C. NEWTONCLARKE F. MILLETTEJohn Wiley & Sons, Inc.Journal of Andrology...
Description Previously immortalized sertoli cells- involved in androgen regulation during spermatogenesis- lose androgen receptor (AR) expression or androgen responsiveness; thus leaving them ill-suited for any further research regarding androgen regulation. The Immortalized Mouse Sertoli Cells (ST38c) eliminat...
Which pathway plays a decisive role when the TGF-β/Smad, AMPK, and MAPK signaling pathways in Sertoli cells regulate the same process? What are the detailed molecular downstream mechanisms and interactions of proteins involved in the pathways mediating physiological functions of Sertoli cells?
Spermatogonia, which produce sperm throughout the male lifetime, are regulated inside a niche composed of Sertoli cells, and other testis cell types. Defects in Sertoli cells often lead to infertility, but replacement of defective cells has been limited by the inability to deplete the existing pop...
A healthy man typically produces between 50 × 106 and 200 × 106 spermatozoa per day by spermatogenesis; in the absence of Sertoli cells in the male gonad, this individual would be infertile. In the adult testis, Sertoli cells are...
Only Sertoli cells are present in the seminiferous tubule. This is the most severe phenotype. In this case, the individual shows azoospermia as the consequence of a complete absence of germ cells in the tubules. – Germ-cell maturation failure. The process of spermatogenesis was tot...
Sertoli cellsWNT3Contents The proliferation and differentiation ability of testicular Sertoli cells directly affects spermatogenesis and male reproductive development. WNT proteins are involved in the regulation of cell proliferation, differentiation and spermatogenesis. Therefore, to study whether lncRNAs, which...