cloning and detection of serpin-like protein encoding gene in Bifidobacterium lon-gum strains. Nissen L,Pasini L,Biavati B,et al. Annals of Microbiology . 2008Nissen L,Pasini L,,Biavati B,et al.Cloning and detection ofSerpin-like protein encoding gene inBifidobacterium longumstrains. Annals ...
We purified a novel serine proteinase inhibitor (serpin)-like protein from the bovine brain and named it B-43 from its molecular mass, 43 kDa. A cleaved peptide from B-43 was copurified with the native B-43. Partial amino acid sequencing of the purified B-43 showed that this protein ...
Translation of this open reading frame, designated MYXOMA SERPIN 1 (SERP1), reveals a protein sequence with highly significant homology to the super-family of serine protease inhibitors (serpins) which also includes a number of other poxviral proteins. In the MYX genome the SERP1 gene lies ...
Pso p27, a SERPINB3/B4-derived protein, is most likely a common autoantigen in chronic inflammatory diseases 2017, Clinical Immunology Show abstract The putative role of Rhipicephalus microplus salivary serpins in the tick-host relationship 2016, Insect Biochemistry and Molecular Biology Citation Excer...
Using recombinant DNA techniques, we prepared a fusion protein of glutathione S-transferase and full-length SCCA2. The recombinant SCCA2 was most effective against two chymotrypsin-like proteinases from inflammatory cells, but was ineffective against papain-like cysteine proteinases. Serpin-like ...
- 《Protein Engineering》 被引量: 133发表: 1997年 Characterization of an Exo-β-D-Glucosaminidase Involved in a Novel Chitinolytic Pathway from the Hyperthermophilic Archaeon Thermococcus kodakaraensis KOD1. We previously clarified that the chitinase from the hyperthermophilic archaeon Thermococcus kodak...
We performed behavioral tests (open field, suspension and pole-climbing tests) to observe Mn-induced motor changes, immunohistochemistry to detect Mn-induced midbrain changes, and Western blot to detect Mn-induced changes of protein expression. It was found that Serpina3n KO markedly alleviated Mn...
PARs, which are members of the G protein-coupled receptor superfamily, are activated upon cleavage of their extracellular N-terminus to unmask a tethered receptor-activating sequence (PMID: 22453980). However, the role(s) of PARs and their activating proteinases in a microglial cell environment ...
MNEI (monocyte/neutrophil elastase inhibitor) is a 42 kDa serpin superfamily protein characterized initially as a fast-acting inhibitor of neutrophil elastase. Here we show that MNEI has a broader specificity, efficiently inhibiting proteases with elastase- and chymotrypsin-like specificities. Reaction ...
Irving JA, Miranda E, Haq I, et al. An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein. Biochem J. 2015;468(1):99-108. doi: https://doi.org/10.1042/BJ20141569Irving JA, Miranda E, Haq I, Perez J, Kotov VR, Faull SV, ...