Serotonin syndrome caused by interaction between citalopram and fentanyl Objective: To report a case of serotonin syndrome associated with interaction between fentanyl and citalopram, as evidenced by medication history, clinical... S Ailawadhi,KW Sung,LA Carlson,... - 《Journal of Clinical Pharmacy ...
Diagnosis : There is no laboratory test for diagnosing Serotonin syndrome; therefore, diagnosis is purely clinical and relies on patient presentation, symptom observation, medication history, physical examination, patient history, and the ruling out of other neurologic disorders such as meningoencephalitis...
Serotonin syndromeTramadolSetting: University-based outpatient clinic. Participant: A 57-year-old woman with chronic low back pain (CLBP) due to lumbar radiculopathy. Case Description: The patient, who had a medical history of hypothyroidism, hypertension, peptic ulcer disease, major depression, ...
Serotonin syndromeresults from excessive stimulation of central and peripheralserotonin receptors, particularly 5-HT2Areceptors. Unlike NMS,serotonin syndromeis a dose-dependent phenomenon and develops rapidly following administration of single doses of, or combinations of, drugs that enhance serotonergic tran...
SerotoninSyndromeSSRIs,SNRIs,Triptans,andCurrentClinicalPracticeAbstractandIntroductionIntroductionSerotoninsyndrome(S..
Treatment consists primarily of discontinuing the offending medication, which results in the rapid resolution of symptoms. Resolution may be more gradual with medications such as fluoxetine, due to their long half-life. Supportive care is the mainstay, and mild cases of serotonin syndrome can be ma...
ChIPS—children's interview for psychiatric syndrome CMDA—cortico-mesolimbic dopamine DA—dopamine DDD—drinks/drinking day DSM—Diagnostic and Statistical Manual of Mental Disorders EOA—early-onset alcoholic(s) G2651T—a site within a putative polyadenylation signal for a commonly used 3′ polyadenyla...
In 2006, the US Food and Drug Administration (FDA) issued an advisory about the risk of serotonin syndrome associated with concomitant use of drugs from 2 widely prescribed medication classes: (1) selective serotonin reuptake inhibitor (SSRI) and selective norepinephrine reuptake inhibitor (SNRI) ...
Selective serotonin reuptake inhibitors in pregnant women and neonatal withdrawal syndrome: a database analysis. Lancet 365: 482–487. Spielberger CD, Gorsuch I, Lushene RE (1970). Manual for the State-Trait Anxiety Inventory. Consulting Psychologists Press: Palo Alto, CA. ten Hof J, Nijhuis ...
As clinicians become more aware of serotonin syndrome, and as drug combinations become more common, it is possible we will see more cases of toxic interactions involving trazodone combinations in the literature. Nefazodone–SSRI interactions have not been well described in the literature. There are...