What is the state of the art of 25 years later? Is 5-HT related to depression, or to certain features of depression, or is it not?doi:10.1007/978-1-4684-8329-1_18H. M. van PraagSpringer US
Results: Depression is more common in women than in men and seems to be increased at times of changing hormone levels in women. The serotonergic system seems to play a major role in depression, although other neurotransmitters are also involved. Estrogen can alter not just serotonergic activity ...
According to the monoaminergic theory, depression is due to a deficit of dopamine and/or serotonin release in the brain, which induces characteristic affective, cognitive, and behavioral deficits. From:Archives of Medical Research,2000 About this page ...
Dysregulation of peripheral serotonin, common to both depression and CHD, may contribute to this association. METHODS: We performed a cross-sectional study of 791 participants with stable CHD enrolled in the Heart and Soul Study and not taking antidepressant medication. We assessed major depression ...
Related on Be Brain Fit — The Role Sugar Plays in Depression and Anxiety Four Foods That Increase Serotonin Naturally A handful of foods do not contain serotonin but work by a variety of other mechanisms to increase serotonin naturally.
Researchers think a lack of serotonin in your brain may play a role in depression. However, too much of it can lead to extreme nerve cell activity and dangerous symptoms. Serotonin syndrome vs. NMS Neuroleptic malignant syndrome (NMS)is similar to serotonin syndrome. This condition is rare but...
Effects were dose-dependent and not related to side effects (few and mild) or changes in anxiety or depression (not observed). SUI also decreased desire to drink and liking for alcohol, thus suggesting a mechanism for effects. Other drugs acting on the 5-HT system have been tested in ...
Chronic stress and dysfunction of the serotonergic system in the brain have been considered as two of the major risks for development of depression. In the present study, adult Fischer 344 rats were subjected to a regimen of chronic social defeat (CSD). To mimic stressful conditions some rats ...
These effects have been reproduced in both depressed patients and animal models of depression7,9,18,19, leading to the classic view according to which 5-HT signalling promotes hippocampal plasticity and elevates mood-related behaviours. However, the generation of 5-HT deficient animal models ...
The Interaction of Stressful Life Events and a Serotonin Transporter Polymorphism in the Prediction of Episodes of Major Depression: A Replication Prior evidence from twin studies suggested genetic moderation of the depressogenic effects of stressful life events (SLEs). Can the specific genes involved....