Serotoninis aneurotransmitterand serves critical cognitive and behavioral functions in humans, with numerous important peripheral functions in the gut, vasculature, immune system, and atwoundsites[168–170]. Serotonin is well known for its role as a neurotransmitter involved with mood regulation; but ...
SUMMARY Sertraline is a potent and specific serotonin uptake inhibitor with efficacy in mood and anxiety disorders. Its therapeutic value in major depression, dysthymia, OCD, social phobia, panic disorder, and PMDD has been established. In addition, recent data support its relative safety for use ...
α (3-hour post-IFN-α cortisol response minus baseline) (r= −.72,n= 14,p< .01). Taken together, these findings regarding the role of CRF andserotonin pathwaysin the pathophysiology of IFN-α-induced mood/cognitive syndrome support the notion that this syndrome is similar, if not the...
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Serotonin, inhibition, and negative mood. PLoS Comput Biol 4: e4. Theoretical assault on the apparent contradiction between the opponency-based suggestion that serotonin is involved in reporting aversive contingencies, and yet boosting, rather than suppres- sing; it is a treatment of choice in ...
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Serotonin, inhibition, and negative mood. PLoS Comput Biol 4: e4. Dayan P, Yu AJ (2006). Phasic norepinephrine: a neural interrupt signal for unexpected events. Network 17: 335–350. Clever integration of the roles of serotonin in behavioral control and the learning from negative events as ...
Incomplete symptom remission and sexual side effects are common problems for which bupropion often is added to treatment with selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs) for patients with major depressive disorder (MDD). This article reviews the literature on ...
(Myers, 1980), endocrine regulation (Montagne and Calas, 1988), motor activity (Williams and Azmitia, 1981; Jacobs and Azmitia, 1992; Jacobs and Fornal, 1993), pain modulation (Le Bars, 1994), learning and memory (McEntee and Crook, 1991), mood (Soubrie, 1988; Maes and Meltzer, 1995...
in the hippocampus and amygdala where it has been assumed to be involved in the regulation of mood and anxiety. This receptor is a target for anxiolytic and antidepressant drugs (Hamon 1997; Blier and De Montigny 1997; Kaufman et al. 2016). 5-HT1A-Rs are preferentially coupled to Gi/o ...