Rabbit head bobs and rodent head twitches are behavioral assays of serotonin (5-HT)2A receptor activation; each behavior can be elicited by DOI (a 5-HT2A/2C agonist) and attenuated by ketanserin (a 5-HT2A antagonist). 5-HT2A receptor antagonists (M100) and (MDL) also elicit head bobs...
Principal Names:HTR2C, 5-hydroxytryptamine (serotonin) receptor 2C, HGNC:5295, 5-HT2C, HTR1C, RP11-810O3.1, 5-HTR2C, OTTHUMP00000023868, serotonin 5-HT-2C receptor, serotonin receptor 2C Official Symbol:HTR2C Accession Number(s):NP_000859.1 ...
This review provides an overview of the role of central serotonin2C(5-HT2C) receptors in drug addiction, specifically focusing on their impact on the neurochemical and behavioral effects of cocaine, one of the most worldwide abused drug. First, we described the neurochemical and electrophysiological...
Administration of the 5-HT2C receptor antagonist SB242084 increased premature responding in the 5-choice serial reaction time task (5-CSRTT), a paradigm used to evaluate the features of behavioral control, including visuospatial attention, response inhibition, and reaction latencies in animal models (...
5-HT receptor subtypes listed:5-HT1A,5-HT1B,5-HT1D,5-HT1F,5-HT2,5-HT2A,5-HT2C,5-HT4,5-HT5A,5-HT6,5-HT7 [1]Recherches sur les diméthylaminopropyl-N phénothiazines substituées. Charpentier P, Gailliot P, Jacob R, et al. Comptes rendus de l’Académie des sciences (Paris)...
A non-synonymous single nucleotide polymorphism of the human serotonin 5-HTreceptor (5-HTR) gene that converts a cysteine to a serine at amino acid codon 23 (Cys23Ser) appears to impact 5-HTR pharmacology at a cellular and systems level. We hypothesized that the Cys23Ser alters 5-HTR ...
Serotonin 2C receptor antagonists are putative fast-acting antidepressants. effects, we hypothesized that 5-HT2C antagonists could be compounds with fast-acting antidepressant potential.;To test this hypothesis, we assessed the time... MD Opal - The University of Chicago. 被引量: 0发表: 2013年 ...
5-HT2c receptor GPCR heterodimer [prove receptor dimer req for serotonin IP second messenger]HerrickDavis, K
Serotonin5-HT2Creceptor-independentexpressionofhypothalamicNOR1, anovelmodulatoroffoodintakeandenergybalance,inmice KatsunoriNonogaki a,b, * ,TakaoKaji b ,YukieOhba a ,MakikoSumii a ,MamoruWakameda c , TomohiroTamari c a CenterofExcellence,DivisionofMolecularMetabolismandDiabetes,TohokuUniversityGraduateSc...
5-HT2A, a G-protein coupled receptor, is widely expressed in the human body, including in the gastrointestinal tract, platelets and the nervous system. It mediates various functions, for e.g. learning, memory, mood regulation, platelet aggregation and va