Bron, J.M. van Dijl, Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus subtilis, J. Biol. Chem. (2000) 25102 - 25108.Tjalsma, H., A. G. Stover, A. Driks, G. Venema, S. Bron, and J. M. van Dijl. 2000a. ...
A group of type II integral serine proteases, including dipeptidyl peptidase IV (DPP4/CD26), seprase/fibroblast activation protein Wen-Tien,ChenThomas,Kelly - 《Cancer & Metastasis Reviews》 被引量: 154发表: 2003年 Stromal expression of fibroblast activation protein/seprase, a cell membrane serine...
We have previously shown that the Kunitz-type serine protease inhibitor Spint1a, also named Hai1a, is required in the zebrafish embryonic epidermis to restrict the activity of the type II transmembrane serine protease (TTSP) Matriptase1a/St14a, thereby ensuring epidermal homeostasis. A closely relat...
Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2The type II membrane-anchored serine protease, matriptase, encoded by() regulates the integrity of the intestinal epithelial barrier in concert with its...
Oligopeptidase B: a new type of serine peptidase with a unique substrate-dependent temperature sensitivity. Biochemistry 38, 15548-15555.Polgár L.Oligopeptidase B: a new type of serine peptidase with a unique substrate-dependent temperature sensitivity. Biochemistry . 1999...
In the light of steadily increasing rates of antimicrobial resistance, we have developed novel macrocyclic lipopeptides, linking P2 and P1' by a boronic ester warhead, capable of inhibiting Escherichia coli type I signal peptidase (EcLepB) and exhibiting good antibacterial activity. Structural ...
Iβ cGK (130 µg) was treated with endoproteinase Lys-C peptidase (sequencing grade) for 30 min at 30°C at a 1:30 ratio (w/w) of protease to enzyme in the presence of 10 µM cGMP. The extent of the digest was assessed using 10% SDS-PAGE. A portion of the digest (18 ...
Polyprotein processing of dengue virus type 2, a positive strand RNA virus, is carried out by the host signal peptidase and a novel two-component viral proteinase of the serine proteinase family, NS2B/NS3(Pro), in the endoplasmic reticulum. Using an in vitro processing system, we examined ...