Sequential parallel comparison design (SPCD) can be used to address this problem. However, the SPCD has not yet been discussed in relation to clinical trials with coprimary endpoints. In this article, our aim wa
Royalty/patent, other income: Patents for Sequential Parallel Comparison Design (SPCD), licensed by MGH to Pharmaceutical Product Development (PPD); and patent application for a combination of Ketamine plus Scopolamine in Major Depressive Disorder (MDD), licensed by MGH to Biohaven.Dr Gueorguieva ...
For a parallel comparison of various platforms using the same lysed pseudovirus test sample, we used commercially available rapid diagnostic test (RDT) kits (Flowflex® COVID-19 Antigen Home Test, USA) for COVID-19, following the kit's instruction manual. The photographs of the test results...
MapReduce [2], [3] is a programming model that allows easy development of scalable parallel applications to process large scale data on a large cluster of commodity machines [4]. Apache Hadoop [5], [6], as an open-source implementation of MapReduce framework has been used in many fields...
d, peCHYRON recording cell lines were created from 293 T and SV40-immortalized mouse embryonic fibroblasts in parallel and grown for 15 days. Two technical replicates for each of two biological replicates are shown. Source data Extended Data Fig. 7 Recording of transfection order with peCHYRON...
Performance comparison of traditional CNN with proposed LHQNN models on a MNIST and b Fashion-MNIST data Full size image The performance analysis curve for non-sequential LHQNN with amplitude embedding is illustrated in Fig. 9a and b. The validation loss reached a minimum of 0.2592 after eight ...
question, with researchers claiming that sequential lineups do not induce more accurate identifications, just less identifications overall (for a review, see Gronlund et al.,2015). A parallel discussion has focused on the comparison between different kinds of sequential lineup procedures and the ...
Cross-domain sequential recommendation baselines: (1)\(\pi\)-Net [45] is the pioneering work of CDSR, which designs a new gated recurrent unit to model and transfer knowledge in different domains. (2)PSJNet [46] is an extension of\(\pi\)-Net, which introduces a parallel split join sch...
Even if the target system is a single sequential machine, it is often advantageous to model it as a set of processes running in parallel: • usually the functionality suggests a certain decomposition into modules; sequentialization is not the primary issue in the design; • certain sub...
Despite the recent achievements in urea electrosynthesis from co-reduction of nitrogen wastes (such as NO3−) and CO2, the product selectivity remains fairly mediocre due to the competing nature of the two parallel reduction reactions. Here we report a catalyst design that affords high selectivity...