Structure variant accuracy and recall assessment The assessment of different SV callers and mergers was conducted using the ‘bench’ module in Truvari software (v3.0.0)29, with the following parameters: ‘bench -p 50 -P 50 -r 500’. To evaluate the performance of SV callers, we compared...
WRN’s C-terminal region, downstream of its helicase domain, contributes to these structure and sequence preferences. Our results strongly suggest that WRN specifically acts in telomeric HR processes possibly including T-loop formation. Results Preferential action of WRN on strand invasion intermediates ...
Genomics focuses on deciphering genome sequences and analyzing genome structure, function, polymorphisms, and evolution. 3.3.1 Introduction of next-generation DNA sequencing DNA sequencing is a method that determines the order of bases in a DNA molecule, and the sequencing data provide the basic and...
The vaccinia virus 14-kilodalton (A27L) fusion protein forms a triple coiled-coil structure and interacts with the 21-kilodalton (A17L) virus membrane prot... The vaccinia virus 14-kDa protein (encoded by the A27L gene) plays an important role in the biology of the virus, acting in virus...
Edward T Maggio, Kal Ramnarayan, in Trends in Biotechnology, 2001 As the sequence homology between the modeled protein and the template structure of the appropriate fold class derived from X-ray crystallography is lowered, the accuracy of the model degrades. There is an effective low-end cut-...
Pengfei, Dong Bo, Cui Ling. 2010.Application of sequence stratigraphy in prediction of lithologic reservoirs:A case study of the Lower Member of Xiaganchaigou Formation in Qigequan area, southwest of Qaidam Basin[J]. Journal of Yangtze University (Nat. Sci. Edit), (2):216-219(in Chinese...
cmap_type: choices=["C_alpha", "C_bert"], the calculation type of 3D-structure contact map cmap_thresh: the distance threshold (Unit: Angstrom) in contact map calculation. Two amino acids are linked if the distance between them is equal to and less than the threshold, default: 10.0. ou...
RNA sequences evolve more rapidly than the structure they are forming, because their evolutionary behavior follows the structure-function paradigm: RNA molecules with different sequences but same or similar secondary structure are likely to belong to the same functional family, in which the secondary ...
Biological sequence clustering is a complicated data clustering problem owing to the high computation costs incurred for pairwise sequence distance calculations through sequence alignments, as well as difficulties in determining parameters for deriving r
2. In the absence of such a temporal structure, an episode would amount to no more than a random list of details. ‘Mental time travel’, the ability to re-experience past episodes3,4and the ability to simulate future episodes using past events as templates5both rely on the coherence ...