Exon lengthening in GC-rich vertebrate regions does not result, however, in longer vertebrate proteins, perhaps because of the lower number of exons in the genes located in these regions. The effects on coding-
DNA can determine where and when genes are expressed, but the full set of sequence determinants that control gene expression is unknown. Here, we measured the transcriptional activity of DNA sequences that represent an ~100 times larger sequence space th
S1). For instance, about 50% of the human genome consists of repeats5, while roughly 4% of human genes harbor transposable elements in their protein-coding regions6. Because many of these repeats (~89.5%) are located within introns, they have been erroneously assumed to be non-functional7....
Usually refers to a generator function, but may refer to a generator iterator in some contexts. In cases where the intended meaning isn’t clear, using the full terms avoidsambiguity. 提练重点: 1、它是一个迭代器 2、它是一个含有特殊关键字 yield 的迭代器 ...
The overall role of non-coding variants in tumorigenesis is currently likely underestimated as only a handful of genome-wide studies of tumours have analysed them. However, current and future efforts involving large-scale whole-genome sequencing of tumours are likely to shed more light on the impor...
# RNAcode --outfile results.gtf --gtf --best-only --cutoff 0.01 Create color annotations for high scoring coding segments: # RNAcode --eps data.aln 2.2 Input alignment --- The input alignment needs to be formatted in ClustalW format or MAF format (http://genome.ucsc.edu/FAQ/FAQformat...
in the meaning of the invention, acts as a specific molecule, directly, or via a linker, coupled covalently to the phage coat protein pIII of the filamentous phage M 13 as a fusion protein on the surface of phages, incubating the library phages including the phages expressing the fusion prot...
In a eukaryote, a sequence of DNA that codes for a polypeptide will be made up of something known as exons and introns, meaning the sequence of nucleotides will usually not be continuous and will instead be split up into segments.
Meaning of obtaining high quality sequences The focus of this strategy lies on applications where secure base-calling and high quality sequence data are mandatory for interpretation. It is well known that mitochondrial mutations associated to disease such as mitochondrial encephalomyopathies occur in he...
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