Stormo GD. An introduction to sequence similarity ("homology") searching. Curr Protoc Bioinformatics. 2009;27:Chapter 3:Unit 3.1:3.1.1-7.Stromo GD. 2009. An introduction to sequence similarity (“homology”) searching . Curr. Protoc. Bioinformatics 27 :3.1.1–3.1.7. 10.1002/0471250953.bi...
Sequence homology refers to the degree of similarity in the genetic sequences of different proteins or molecules. In the context of the provided text, high sequence homology among Neurotrophins (NTs) made it challenging to develop specific antibodies for Brain-Derived Neurotrophic Factor (BDNF). ...
An Introduction to Sequence Similarity ("Homology") Searching Sequence similarity searching, typically with BLAST, is the most widely used and most reliable strategy for characterizing newly determined sequences. Sequ... WR Pearson - Current protocols in bioinformatics / editoral board, Andreas D. Ba...
bioinformaticspymol-pluginpymolprotein-sequencessequence-alignmentshomology-modelingprotein-structuresstructural-alignmentssimilarity-searches UpdatedMay 29, 2024 Python sbl-sdsc/mmtf-pyspark Star67 Code Issues Pull requests Methods for the parallel and distributed analysis and mining of the Protein Data Bank...
The third group comprises unique, single-copy DNA sequences, which do not share homology with any other sequences in the genome. Examples of such sequences in the human genome include protein-coding genes (e.g., theglobin,ovalbumin, andsilk fibroingenes), non-coding RNAs, and regulatory ele...
cagnagella and combined the results with transcriptomic and proteomic analyses and a homology searches using proteins detected in Y. evonymella. Results Y. cagnagella genome. The genome size of Y. cagnagella was determined by flow cytometry. Four heads of adult males were used with Ephestia ...
One approach toward determining homology entails the use of sequence-alignment algorithms that maximize the similarity between two sequences. For homology modeling, these alignments could be used to obtain the likely amino-acid correspondence between the sequences. Introduction Sequence alignment identifies...
[1]. Annotation of a genome involves assignment of functions to proteins in most cases on the basis of sequence similarity. Protein function assignments based on postulated homology as recognized by sequence identity or significant expectation value of alignment are used routinely in genome analysis. ...
Nuclear Magnetic Resonance, BiomolecularNucleic Acid ConformationProtein ConformationSequence Homology, Nucleic AcidThermodynamicsThe solution structure of an ... MJJ Blommers,F Natt,W Jahnke,... - 《Biochemistry》 被引量: 313发表: 1998年 Dual amino acid-selective and site-directed stable-isotope label...
Multiple surveys have been published that compare the performance of methods for remote homology detection and structure prediction (see [5–11] for the recent ones). To assess the quality of similarity detection from sequence, workers generally use a set of protein domains from an established ...