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Since protein function depends on 3D shape, important regions are often spread throughout the sequence and are not just located at termini. This makes GPT models less effective for many practical design tasks. Indeed, the complex and long-range interactions between different parts of the protein ...
Hi I am using Microsoft Office 2019 and already updated it. But I still can't use the sequence function Poobalan Google "excel sequence function" and read (click here)😞:
My ultimate goal is to create a plot showing the max, min and mean data vs time or frame (image number) for multiple objects in the batch of images. The objects could be moving at bit (video of worms) but my thinking is to create a mask to seperate the obje...
A cGAN-based flanking sequence generation model was adopted in DeepSEED to estimate\(P\left(f | {m}^{*}\right)\)(see “Objective function” in “Methods”). Attention-based layers were applied because of their ability to capture the widespread long-range interactions in regulatory codes. A...
Since protein function depends on 3D shape, important regions are often spread throughout the sequence and are not just located at termini. This makes GPT models less effective for many practical design tasks. Indeed, the complex and long-range interactions between different parts of the protein ...
and dual-function TFs (Sp1) that can activate or repress transcription initiation in a position-dependent manner.f, Position-dependent activity was evaluated for mutations impacting 463 known human TF motifs (not all are expressed in BMDMs). A detailed map of this figure is provided in Supplement...
Structure-function relationships between phosphomonoesterase-specific PPPs and other branches of the MPE superfamily appear to reflect in part the modification of ancestral forms to confer specificity for phosphoserine, phosphothreonine and phosphotyrosine phosphate monoester substrates over cyclic and linear ...
This report provides the first molecular foundation for the model that the CFBP linker acts as an unstructured, flexible loop, allowing the two flanking chaperone modules function independently while linked in cis, likely to assist in the folding of multisubunit client complexes. Graphical Abstract ...
Further, let PMAX ("parallel maxima") be a function that reduces a list of equal-length vectors to a single vector by determining the maximum for each vector position: PMAX(a, b, . . . ) := (max(a1, b1, . . . ), . . . , max(an, bn, . . . )) for a = (a1, . ...