1 showed the schematic diagram for the synthesis of the sequence-defined conjugated oligomers. In the presence of catalyst palladium acetate (Pd(OAc)2), RuPhos ligand, and anhydrous potassium phosphate (K3PO4), the coupling reaction between 4-bromo-3-hexylthien-2-yl-MIDA boronate and excessive...
a Schematic diagram of PairExplainer working principle: For both DUB and substrate, a sliding window of 3 residues moves along the protein sequence with a step size of 1 residue, performing in silico “knockout” by removing all residues except for the triad within the sliding window. The reg...
A, Venn diagram for all differentially expressed genes from NHEKs treated with U1 dsRNA, LL-34-parent, and combinations of either U1 dsRNA and LL-34-parent. B, Venn diagram for showing genes differentially regulated in cells treated with U1 dsRNA and LL-34-I24A versus LL-34-I24A and ...
A global genetic interaction network maps a wiring diagram of cellular function Science, 353 (2016), p. aaf1420 Google Scholar 19 M.C. Jonikas, S.R. Collins, V. Denic, E. Oh, E.M. Quan, V. Schmid, et al. Comprehensive characterization of genes required for protein folding in the en...
The free mRNAs generated from cDNA vectors are more likely to be targeted for nuclear degradation and/or inefficient export. (B) Diagram showing Lac operon-controlled luciferase chimeric vectors. (C) Y-1 cells stably expressing the Lac repressor gene were transiently cotransfected with vectors ...
b Venn diagram analysis of identified readers for mC, hmC, fC, and caC modifications in hemi- form. c Venn diagram analysis between symmetric and hemi-modification readers in the context of mCpG, hmCpG, fCpG, and caCpG modifications. d The identified binding activities to both symmetric and...
This diagram was based on the consensus responses observed in Fig. 6b. d Northern blot validating the level changes of TUT4 and TUT7 regulated miRNAs in WT, DKO, and TKO cells. e Northern blot validating TUT4 and TUT7 rescue effects on the levels of TUT4 and TUT7 regulated miRNAs. f...
FIG. 3 is a flowchart illustrating a method of designing probes for detecting target sequence according to an embodiment of the present invention; FIG. 4A is a schematic diagram illustrating an example of selecting an anchoring location according to an embodiment of the present invention; ...
FIG. 3 shows a flow diagram for a method for providing enriched nucleotide sequence data 36. The method of FIG. 3 differs from the method of FIG. 2 in that the step S12 performed by the pre-processing unit 14 is replaced by the two steps S18 and S20. In the case shown in FIG. ...
FIG. 1 is a diagram illustrating the positions of target sequences of the genomic RNA of norovirus; FIG. 2 is a view illustrating an array of spots of oligonucleotide probes immobilized on a microarray substrate; and FIG. 3 is an image showing hybridization results of oligonucleotide probes imm...