DNA can determine where and when genes are expressed, but the full set of sequence determinants that control gene expression is unknown. Here, we measured the transcriptional activity of DNA sequences that represent an ~100 times larger sequence space th
Venn diagram of variants detected by various aligners. a Accel-align (25-mer), b BWA-MEM, c Minimap2, d Bowtie2, e Subread Full size image In order to isolate and understand the behavior of Accel-Align in the presence of SNP and INDEL variants, we show the F-score for SNP and IN...
For each one of the different metrics, there must be a different neural network, which is trained in an independent process. In this case, there will be five different networks, one for each usability attribute established. Figure 3 shows the complete diagram. Figure 3. Diagram of the ...
Encouraged by the previous investigators’ studies, here we are also developing an ensemble classifier by fusing the seven individual predictors ℝ𝔽(𝑘) (𝑘=1,2,⋯,7)ℝF(k) (k=1,2,⋯,7) through a voting system, as formulated by: ℝ𝔽E=ℝ𝔽(1)∀⋯∀ℝ𝔽...
The section adds the particulars about the data acquisition setup that is shown in Figure 1, feature extraction process, employed ML techniques and DL architectures, the conceived validation workflows, and the statistics approaches for the performance comparisons. The overall flow diagram of the experim...
52.5 GHz 6-core CPU, 32 GB memory and Windows operating system(Microsoft Corporation, Redmond, WA, USA). Two RF parameters, the number of decision trees and split are 1000 and 30. 2.4. Performance of PPI Prediction We use eight different PPI datasets to evaluate the performance of our ...