From the perspective of the clinical manifestation, autopsy examination and pathophysiology, the essence of COVID-19 should be viewed as a sepsis induced by viral infection, and has the essential characteristics as sepsis induced by other pathogens. Therefore, in addition to etiological and supportive...
Diagnostic framework for viral sepsis. In cases where a patient exhibits infection markers or there is suspicion of an infection, and concurrently has a SOFA score ≥ 2 compared to baseline, it is imperative to exclude bacterial, parasitic, and fungal sources. If viral antigen or nucleic acid...
Diagnostic framework for viral sepsis. In cases where a patient exhibits infection markers or there is suspicion of an infection, and concurrently has a SOFA score ≥ 2 compared to baseline, it is imperative to exclude bacterial, parasitic, and fungal sources. If viral antigen or nucleic acid...
The rising tide of sepsis due to bacterial, fungal and viral infections cannot be stemmed by current antimicrobial therapies and supportive measures. New paradigms for the mechanism and resolution of sepsis and consequences for sepsis survivors are emerging. Consistent with Benjamin Franklin's dictum '...
Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host response to infection that leads to uncontrolled inflammatory response followed by immunosuppression. However, despite the high mortality rate, no specific treatment moda
New research reveals hospital ventilation and air purifiers may unintentionally spread viral particles, increasing infection risks. Infection preventionists must rethink airflow strategies to protect patients and staff. From "Behind the Mask," Infection Control Today's Podcast: Why Cutting Off Health Comm...
Nosocomial Infection About 5% of nosocomial infections may be due to viral infections; however, the incidence may be underestimated because of difficulty in diagnosis and limitations in the availability of diagnostic tools. These viruses include the respiratory viruses (e. g., HSV, CMV), hepatitis...
et al. IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology. Cell 144, 601–613 (2011). Article CAS PubMed Google Scholar Venet, F. et al. IL-7 restores lymphocyte functions in septic patients. J. Immunol. 189, 5073–5081 (2012). An important...
FDA clearance of the Triverity test system for use in emergency triage of patients with suspected acute infection or sepsis. The molecular blood test is the first to identify bacterial and viral infections and provide an all-cause risk evaluation of the likelihood of developing severe illness.Read...
megakaryocytes also participate in inflammatory responses and regulate immune system functions. Sepsis, characterized by life-threatening organ dysfunction due to a dysregulated response to infection, prominently features coagulopathy, severe inflammation, and immune dysfunction as key pathophysiological aspects....