Methods Systematic literature review and international guidelines were used to identify published evidence regarding the treatment of (suspected) sepsis. Results Five adequately designed and powered studies comparing antibiotic treatments in a low-risk community in neonates and young infants in LMIC were ...
The decision on whether to include an antibiotic active against MRSA in an empiric treatment regimen for sepsis and septic shock depends upon (a) the likelihood that the patient’s infection is caused by MRSA, (b) the risk of harm associated with withholding treatment for MRSA in a patient w...
The Surviving Sepsis Campaign (SSC) consensus guidelines recommend treatment for 7 to 10 days, but this is a weak recommendation.5 Use of antibiotics risks the emergence of antimicrobial resistance and antibiotic-associated infections, such as Clostridiodes difficile . Patients may suffer from toxic ...
OBJECTIVES: Compelling evidence has shown that aggressive resuscitation bundles, adequate source control, appropriate antibiotic therapy, and organ support are cornerstone for the success in the treatment of patients with sepsis. Delay in the initiation of appropriate antibiotic therapy has been recognized ...
The aim of study was to create guidelines for empirical antibiotic therapy of sepsis in ICU for unknown causative agent based on antimicrobial susceptibility of causative bacteria. Thirty-two patients with severe sepsis were included in study and from medical records their clinical and microbiological ...
causative organisms of severe sepsis and septic shock, respectively, and these organisms are associated with higher mortality relative to the other organisms [44]. Therefore, special attention needs to be paid to whether or not treatment with the choice of initial antibiotic regimen should be given...
Preliminary results have shown that early initiation of antibiotic therapy in neonates with suspected sepsis seems to reduce both mortality and morbidity [1]. According to guidelines, the treatment should be given as soon as possible and always within 1 h of the decision to treat [49]. The ant...
Management usually involves aggressive fluid resuscitation and antibiotic therapy, with the likelyinvolvement of the critical care team. Inotropes are often used to maintain organ perfusion. Key Points Sepsis is the life-threatening organ dysfunction caused by an abnormal and uncontrolled host response to...
Antibiotic treatment duration for culture-negative sepsis in the pediatric intensive care unit doi:10.1017/ash.2023.502Antimicrobial Stewardship & Healthcare EpidemiologyWehrenberg, KelseyMitchell, MichelleZembles, TracyKe YanLiyun ZhangThompson, Nathan
causative organisms of severe sepsis and septic shock, respectively, and these organisms are associated with higher mortality relative to the other organisms [44]. Therefore, special attention needs to be paid to whether or not treatment with the choice of initial antibiotic regimen should be given...