Sibbald WJ: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine.Chest1992, 101(6):1644–1655. ...
Compliance with a sepsis care pathway and its impact on morbidity and mortality in gynecologic oncology patientsdoi:10.1016/j.ygyno.2019.04.333T.K.L. BoitanoM.G. CoxA. XhajaH.J. SmithJ.M. StraughnGynecologic Oncology
Mounting evidence in both animal models and human studies suggests that sepsis induces a higher mortality, cognitive decline (e.g. dementia), progressive immunosuppression, cholinergic anti-inflammatory deficiency, metabolic and hydroelectrolyte imbalance. As thus, it causes a great global healthcare burd...
This feasibility study aimed to utilise routinely collected data from electronic health records (EHR) to assess the sepsis inpatient care pathway. We conducted a retrospective observational cohort study which included all patients admitted to a private teaching hospital between 2015 and 2018. De-...
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Impact of Event Scale-6 SCCM : Society of Critical Care Medicine ICBT : Internet-based Cognitive Behavioral Therapy COVID-19 : Coronavirus disease 2019 cCBT : Computerized cognitive behavioral therapy NET : Narrative exposure therapy SAD : Sepsis-associated delirium CAM-ICU : Confusion As...
2130Citations 89Altmetric Metrics Abstract Sepsis is a condition that results from a harmful or damaging host response to infection. Many of the components of the innate immune response that are normally concerned with host defences against infection can, under some circumstances, cause cell and tiss...
More potent and selective PARS inhibitors are needed to elucidate the role of a PARS-dependent pathway in a clinically relevant models of sepsis... M Theisen,K Tr?Ger,I Tugtekin,... - 《Intensive Care Medicine》 被引量: 21发表: 2001年 Established...
(HK1, HK2, and HK3) were upregulated in critically ill patients. HK is involved in the conversion of glucose into glucose-6-phosphate, the very first step in the glycolysis pathway. An increase in pyruvate kinase M2 (PKM2) is also observed. This enzyme is involved in the final step of ...
(TLRs), C-type lectin domain family 7 member A (dectin 1) and C-type lectin domain family 6 member A (dectin 2). Once activated, the subsequent signaling pathways converge toward interferon regulatory factor (IRF) and nuclear factor-κB (NF-κB). IRF is responsible for type I interferon...