(ScvO2) ≥70%早期目标导向治疗流程图 Sepsis Resuscitation BundleTo be started immediately and completed within 6 hours1 blood cultures2 antibiotics3 early goal-directed therapy indicators6hr Bundle Hosp Mortality49%Mortality50%P=0.0123%30%10%6hr bundle yes6hr bundle noSepsis Management BundleTo be...
1.体温>380C或<360C 2.心率>90次/分钟 3.呼吸急促，频率>20次/分，或过度通气，PCO2<30mmHg 4.血白细胞计数>1.2万或<9000或未成熟中性粒细胞比例大于10% 概念 严重脓毒症：指脓毒症伴有器官功能障碍或组 织灌注不良组织灌注不良：乳酸升高或少尿脓毒性休克：充分液体复苏后仍持续低血压 分类 脓毒症(...
概念 脓毒症：（sepsis）是指由感染引起的全身炎症反应综合征（SIRS） SIRS：是指机体对不同原因的严重损伤所产生的系统性炎症反应，并至少具有以下临床表现中的两项：体温>380C或<360C心率>90次/分钟 1.2.3.4.呼吸急促，频率>20次/分，或过度通气，PCO2<30mmHg 血白细胞计数>1.2万或<9000或未...
Crit Care Med 2003;31:946-955.38Early Goal Directed TherapyEarly Goal Directed Therapy.39早期复苏早期复苏 脓毒症导致的休克定义为组织的低灌注,在进行早期复苏的最初6 小时内,复苏目标包括以下方面: (1)中心静脉压(CVP):812 mmH (2)平均动脉压(MAP): 65 mmHg (3 )尿量: 0.5 mLkg-1hr-1。 中心...
“tight glucose control” in critically ill patients with severe sepsis and septic shock. A similar quasi-experimental study in Spain showed that compliance with the resuscitation bundle was more important than the maintenance bundle [301]. Based on these results and the aforementioned controversies, ...
诊治要点概述 2 LOGO 第一部分 诊断要点 1.1 严重全身性感染与感染性休克 SepsisSevereSepsisSepticShock SIRS 非特异性损伤引起的临床反应满足≥2条标准：T>38℃或<36℃HR>90bpm SIRS及可疑或明确的感染 全身性感染伴器官衰竭 顽固性低血压 RR>20bpm WBC>12×109/L或<4×109/L或杆状核>10% SIRS=systemic...
SEPSISMODS 菌血症 血源性感染真菌脓毒症 寄生虫病毒其他 其他 SIRS 创伤 烧伤胰腺炎 系统性炎症反应综合征与感染、非感染的关系 概述 菌血症（bacteremia）——细菌出现在血循环中败血症（septicemia）——细菌在血循环中生长繁殖所引起 的全身性疾病（Bone等认为此概念易引起混淆，建议不予采用）毒血症（toxiemia...
Grade E Resuscitation Bundle Severe Sepsis/Septic Shock Bundles 6 hours 24 hours Sepsis Resuscitation Bundle In the event of hypotension and/or lactate 4 mmol /L: Administer a minimum of 20 ml/kg of crystalloid (or colloid equivalent): 1B Use vasopressors for hypotension not responding to ...
Another recent study reported that implementation of multidisciplinary emergency department (ED) sepsis bundle was associated with improved time to achieve key therapeutic interventions and a reduction in 30-day mortality [3]. In other study, the use of a sepsis triage screening tool significantly ...
2014;32:280–1. PubMed Google Scholar Shiramizo SC, Marra AR, Durao MS, et al. Decreasing mortality in severe sepsis and septic shock patients by implementing a sepsis bundle in a hospital setting. PLoS One. 2011;6:e26790. CAS PubMed Central PubMed Google Scholar Barochia AV, Cui...