a one-hour bundle(H1B)management was combined with psychological intervention in patients with sepsis.METHODS This retrospective analysis included 300 patients with sepsis who were admitted to Henan Provincial People's Hospital between June 2022 and June 2023.According to different intervention methods,...
Hour-1 bundle for sepsis [2][20][22] Definition: a group of critical measures that should be performed within 60 minutes of recognizing patients with septic shock or a high pretest probability (PTP) of sepsis. [2][22][23] Five essential elements Obtain serum lactate. Draw blood ...
Finally, while all the authors of the one-hour SSC bundle are well-respected intensivists, unfortunately they are unfamiliar with the challenges of the ED. For most patients, this first hour of resuscitation will occur in...
We compared compliance between subgroups based on the presence or absence of shock (Supplementary Table 1). A similar trend observed in all sepsis patients was also seen in those without shock. However, in patients with septic shock, these difference in bundle elements between the two groups ...
“Sepsis bundle” approach (ACCM/PALS algorithm) In the SSCG 2012, the initial management bundle is advocated to improve the performance quality of adult sepsis care [3]. The recently conducted global prospective observational study (IMPreSS study) demonstrated the survival benefit of compliance with...
Deep Reinforcement Learning (DRL) has been increasingly attempted in assisting clinicians for real-time treatment of sepsis. While a value function quantifies the performance of policies in such decision-making processes, most value-based DRL algorithms
“the 6-h septic shock bundle”, contains all therapeutic steps to be performed within 6 h of the presentation with septic shock: application of vasopressors (for hypotension not responding to initial fluid replacement) in order to maintain a mean arterial pressure (MAP) ≥ 65 mmHg, measurement...
Current supportive strategies for severe sepsis patients may include an early and goal-directed fluid resuscitation bundle, mechanical ventilation, inotropic and vasopressor therapies, blood cell transfusions, anti-fibrinolytics and mechanical ventilation, and possible renal support [91,177]. The primary ...
3 hour sepsis bundle 1. lactate level 2. blood cultures 3. antibiotics 4. 30ml/kg bolus for hypotension (BP<90/60) or lactate >4 mmol/L 6 hour sepsis bundle 1. vasopressor to maintain MAP >65 2. remeasure lactate inotropic medications for shock ...
Fluid administration is a fundamental sepsis therapy and usually comprises a sepsis bundle fluid challenge. However, if the fluid leaks into interstitial space instead of entering the circulatory system, it may cause more harm than good to the patient. Thus, there is a need to increase the ...