Design, Setting, and Participants In this prospective, multicenter cohort study (Sentinel Lymph Node Biopsy vs Lymphadenectomy for Intermediate- and High-Grade Endometrial Cancer Staging [SENTOR] study), accrual occurred from July 1, 2015, to June 30, 2019, with early stoppage because of prespecifie...
No axillary surgery was performed in 6.3% of the participants; 56.4% underwent an initial SLNB and 37.2% received an initial ALND. The mean number of lymph nodes removed was 7.1 (6.7), with a range of 0 to 44 (interquartile range, 9 [2-11]). Women undergoing ALND had a mean of ...
Participants used blue dye + radiocolloid in 79.4%, blue dye alone in 14.8%, and radiocolloid alone in 5.7% of cases, achieving a 98.7% SLN identification rate. Patient factors associated with increased SLND failure included increased body mass index and age, whereas tumor location, stage, ...
Accordingly, trial participants should be comparable to clinical practice patients in both patient and tumour characteristics, and the standard treatment within and outside a trial should be the same. It is ultimately the clinical practice population to whom clinical trial results will be applied, ...
Proceedings of the Consensus Conference on the Role of Sentinel Lymph Node Biopsy in Carcinoma of the Breast April 19–22, 2001, Philadelphia, PA, USA A consensus conference on the role of sentinel node biopsy in breast cancer was held in Philadelphia in April, 2001; the participants included...
Conflicts of Interest None. Ethical approval This article does not describe any studies with human participants or animals performed by any of the authors.Author information Authors and Affiliations Department of Nuclear Medicine, Universitätsklinikum Würzburg, Würzburg, Germany Christina Bluemel, Ken...
Inclusion criteria were: (1) laparoscopic approach in detecting sentinel nodes with a minimal sample size of >10 participants, and publications that provided identification of effectiveness and diagnostic performance of SLN detection techniques; (2) studies that used radiolabeled tracers and/or blue dye...
Research involving human participants, human material, or human data have been performed in accordance with the Declaration of Helsinki. Consent for publication Not applicable. Competing interests The authors declare no competing interests.Additional information Publisher’s note Springer Nature remains ...
Existing studies suggest that sentinel lymph node biopsy (SLNB) may not be reliable in IBC. The use and frequency of SLNB in women with IBC is not well characterized. Objective To determine the frequency and temporal trend of SLNB in patients with IBC. Design, Setting, and Participants This ...
In light of this, we are concerned that omitting axillary surgery might preclude the use of Oncotype DX to predict the added benefit of chemotherapy in some patient population. The majority of participants in this study had hormone receptor-positive, ERBB2-negative breast cancer with primary tumors...