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To investigate the temperature sensitivity of various recombinant viruses, pulse–label and pulse–chase studies were performed. L929 cells were primarily infected with rSeV(PA), rSeV(Mpi), rSeV(HNpi), rSeV(Fpi), or rSeV(Mpi+HNpi) at an m.o.i. of about 10, and after incubation at 32...
AIM: To investigate a novel therapeutic strategy to target and suppress c-myc in human cancers using far up stream element (FUSE)-binding protein-interacting repressor (FIR). METHODS: Endogenous c-Myc suppression and apoptosis induction by a transient FIR-expressing vector was examined in vivo via...
Check access to the full text by signing in through your organization. Access through your organization Section snippets Animals and inoculations Cotton rats (Sigmodon hispidus,≥6 weeks of age) were purchased from Ace Animals (Boyertown, PA). Groups of 2–5 animals were vaccinated with 2 ...