Origin of Self-replicating Biopolymers: Autocatalytic Feedback can Jump-start the RNA World. J Mol Evol. 2009; 69 :541–554. doi: 10.1007/s00239-009-9276-8. [ Cross Ref ]Wu M, Higgs PG. Origin of self-replicating biopolymers: autocatalytic feedback can jump-start the RNA world. J Mol...
Although there is more and more evidence suggested the existence of an RNA World during the origin of life, the scenario concerning the origin of the RNA World remains blurry. Usually it is speculated that it originated from a prebiotic nucleotide pool, during which a self-replicating RNA synthe...
Biebricher, C. K. 1983 In Darwinian selection of self-replicating RNA molecules, vol. 16 (eds M. K. Hecht, B. Wallace & G. T. Prance) Evolutionary biology, pp. 1-52. New York, NY: Plenum Publishing Corporation.Bieberich, C.K.: Darwinian Selection of Self-Replicating RNA Molecules....
This cross-talk plays an important role for the accuracy of the decoding process. Codon–anticodon interaction at the E site seems to be the signal to switch into the post-translocational (POST) state...关键词:origin of life ribosome evolution RNA self‐replication symmetrical region ...
For the initiation of DNA synthesis, all PolBs characterized thus far depend on the presence of an external primer, a hydroxyl group presented either by a nucleic acid (RNA or DNA) or the so-called terminal protein (TP). Thus, based on the primer requirement for the initiation of genome ...
1975 Beta structures of alternating polypeptides and their possible 500 prebiotic significance. Nature 256, 383-387. (doi:10.1038/256383a0) 501 19. Maury CPJ. 2015 Origin of life. Primordial genetics: information transfer in a pre-RNA 502 world based on self-replicating beta-sheet amyloid ...
Experimentally, RNA-like nucleotide polymers containing only uracil [poly(U)] or only cytidine [poly(C)] as bases have been synthesized. The question was then asked: will poly(U) create strings of various nucleotide monomers containing only A's and do so without the presence of protein ...
A crucial stage in the origin of life was the emergence of the first molecular entity that was able to replicate, transmit information, and evolve on the early Earth. The amyloid world hypothesis posits that in the pre-RNA era, information processing was based on catalytic amyloids. The self...
RNA WorldAlthough there is more and more evidence suggested the existence of an RNA World during the origin of life, the scenario concerning the origin of the RNA World remains blurry. Usually it is speculated that it originated from a prebiotic nucleotide pool, during which a self-replicating ...
Rna worldOriginMacromoleculesSelectionChemistrySystemsGrowthLifeHexadeoxynucleotideA mathematical model concerning the origin and the growth of self-replicating polymers is developed. The polymers compete for activated monomers which can be carried into the system under constant or periodic fluxes. Changes in ...